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Role of Initial Procalcitonin in Predicting Mortality in Sepsis

Naveen Mohan , Sona Kurian1 , Naveen Mohan2 , Gireesh Kumar KP3 , Bharath Prasad4 , Dhanasekharan BS5 , Sreekrishnan TP6 , Arun Kumar7

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Indian Journal of Emergency Medicine 6(1):p 15-18, January-March 2020. | DOI: http://dx.doi.org/10.21088/ijem.2395.311X.6120.2

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Sona Kurian, Naveen Mohan, Gireesh Kumar KP, et al. Role of Initial Procalcitonin in Predicting Mortality in Sepsis. Indian J Emerg Med. 2020;6(1):15–18.

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Abstract

Context: There exists a deficiency in literature regarding the importance of procalcitonin in predicting mortality in sepsis patients. Aim: To determine the role of initial procalcitonin in predicting 7-day mortality in sepsis patients. Materials and methods: A prospective observational study was conducted on 200 sepsis patients admitted to the Emergency Department of a Medical College Hospital at Kochi. Blood culture samples and serum procalcitonin samples were withdrawn immediately and sent to lab. Mortality data of those patients were charted at the end of 7 days. Procalcitonin values were compared in both survivors and non survivors using paired Student t-test. p < 0.05 was accepted as statistically significant. Results: Out of the 200 patients, 131 were males and 69 were females. 17% expired and 83% survived at the end of 7 days of hospital stay. Mean procalcitonin value in survivors and non survivors were 16.41 ng/ml and 23.09 ng/ml respectively, which showed statistical significance [p-value = 0.026]. Conclusion: Initial procalcitonin plays an important role in predicting 7-day mortality in sepsis patients. 

Keywords: Sepsis; Procalcitonin; Mortality.

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Sona Kurian, Naveen Mohan, Gireesh Kumar KP, et al. Role of Initial Procalcitonin in Predicting Mortality in Sepsis. Indian J Emerg Med. 2020;6(1):15–18.

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DOI: http://dx.doi.org/10.21088/ijem.2395.311X.6120.2

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