Full Text (PDF)
Indian Journal of Obstetrics and Gynecology 12(2):p 91-94, April - June 2024. | DOI: https://doi.org/10.21088/ijog.2321.1636.12224.7
Case Report
Recent Updates on Carcinosarcoma of the Uterus
Priyanka Yoga Purini, Sharmila V, Abhishek Raghava K S, Poongodi R, Darshan H.N.
Author Information
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Obstetrics and Gynecology 12(2):p 91-94, April - June 2024. | DOI: https://doi.org/10.21088/ijog.2321.1636.12224.7
How Cite This Article:
Priyanka Yoga. Purini, Sharmila V, Abhishek Raghava K S et al. Recent Updates on Carcinosarcoma of the Uterus. Indian J Obstet Gynecol. 2024;12(2):91-94.Timeline
Received : April 30, 2024
Accepted : May 20, 2024
Published : June 30, 2024
Abstract
Carcinosarcoma is a very rare, aggressive malignant neoplasm of the uterus and it is associated with poor prognosis. We are presenting a case of a 66-year-old multiparous postmenopausal women who had bleeding for a period of 3 months. On MRI Imaging there is a 6 cm lesion in the endometrial cavity, biopsy from the endometrium showed carcinosarcoma and she underwent extrafascial hysterectomy with bilateral slapingoophorectomy, omentectomy, and retroperitoneal lymph node dissection. Postoperatively ascites is positive for malignant cells, histopathology of specimen reported as carcinosarcoma FIGO grade 3 and lymph nodes are positive for malignancy. She received adjuvant chemotherapy with carboplatin and paclitaxel.
References
- 1. Anupama R, Kuriakose S, Vijaykumar DK, Pavithran K, Jojo A, Indu RN, Sheejamol VS. Carcinosarcoma of the uterus-a single institution retrospective analysis of the management and outcome and a brief review of literature. Indian J Surg Oncol. 2013 Sep;4(3): 222-8. doi: 10.1007/s13193-012-0206-7. Epub 2013 Jan 27. PMID: 24426726; PMCID: PMC3771046.
- 2. Adachi, Y., Nonogaki, H., Minamiguchi, S., Li, M., & Ikehara, S. (2016). Carcinosarcoma of the uterus: A case report. Molecular and Clinical Oncology, 4, 571-573. https://doi.org/10.3892/mco.2016.744.
- 3. McCluggage WG. Malignant biphasic uterine tumours: carcinosarcomas or metaplastic carcinomas? J Clin Pathol. 2002 May;55(5):321-5. doi: 10.1136/jcp.55.5.321. PMID: 11986333; PMCID: PMC1769650.
- 4. Menczer J. Review of Recommended Treatment of Uterine Carcinosarcoma. Curr Treat Options Oncol. 2015 Nov;16(11):53. doi: 10.1007/s11864-015-0370-4. PMID: 26374341.
- 5. Jaime Prat, ‘Nomonde Mbatani Uterine sarcomas. International Journal of Gynecology & Obstetrics pages: S105-S110 Volume 131Issue S2 First Published online: 11 October 30, 2018 https://doi. org/10.1002/ijgo.12613.
- 6. Bogani G, Ray-Coquard I, Concin N, et al. Int J Gynecol Cancer 2023;33:147–174.
- 7. Tuan HX, Duc NM, Tri CM, Quyen HD, Dung PX. Carcinosarcoma of uterus. Radiol Case Rep. 2023 Jan 15;18(3):1297-1301. doi: 10.1016/j.radcr.2022.12.070. PMID: 36684637; PMCID: PMC9851838.
- 8. Concin N, Planchamp F, Abu-Rustum NR, et al. European Society of Gynaecological Oncology quality indicators for the surgical treatment of endometrial carcinoma. Int J Gynecol Cancer 2021;31:1508–29.
- 9. Abu-Rustum NR, Yashar CM, Bradley K, et al. NCCN Guidelines® insights: uterine neoplasms, version 3.2021. J Natl Compr Canc Netw 2021;19:888–95.
- 10. Matsuzaki S, Klar M, Matsuzaki S, et al. Uterine carcinosarcoma: contemporary clinical summary, molecular updates, and future research opportunity. Gynecol Oncol 2021;160:586–601.
- 11. Raffone A, Travaglino A, Raimondo D, et al. Uterine carcinosarcoma vs endometrial serous and clear cell carcinoma: a systematic review and meta-analysis of survival. Int J Gynaecol Obstet 2022;158:520–7.
- 12. Travaglino A, Raffone A, Raimondo D, et al. Prognostic value of the TCGA molecular classification in uterine carcinosarcoma. Int J Gynaecol Obstet 2022;158:13–20.
- 13. Cancer Genome Atlas Research Network, Kandoth C, Schultz N, et al. Integrated genomic characterization of endometrial carcinoma. Nature 2013;497:67–73.
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
Priyanka Yoga. Purini, Sharmila V, Abhishek Raghava K S et al. Recent Updates on Carcinosarcoma of the Uterus. Indian J Obstet Gynecol. 2024;12(2):91-94.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| April 30, 2024 | May 20, 2024 | June 30, 2024 |
DOI: https://doi.org/10.21088/ijog.2321.1636.12224.7
Keywords
Post menopausal bleedingPolypoidal massCarcinosarcomaMalignant mixed mullein tumourSearch for Similar Articles
Similar Articles
- A Rare Case of Vaginal Vault Endometriosis in a Post Hysterectomised Woman: A Ca...
- An Incidental Dilemma of Degenerated Stony Parasitic Fibroid: A Rare Case Report
- Recurrence Ectopic Pregnancy in the Post Salpingectomy Stump: A Rare Case and Li...
- Obstetric Outcomes of Pregnancy with Uterine Fibroids
- Occupational Predictors of Obstetric and Perinatal Outcomes in Working Women in...
Article Level Metrics
Last UpdatedFriday 10 July 2026, 05:53:44 (IST)
1907
Accesses
9
349
00
Citations
NA
NA
NA
Download citation
Article Keywords
Keyword Highlighting
Highlight selected keywords in the article text.
Timeline
| Received | April 30, 2024 |
| Accepted | May 20, 2024 |
| Published | June 30, 2024 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
