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Case Report

Recent Updates on Carcinosarcoma of the Uterus

Priyanka Yoga Purini, Sharmila V, Abhishek Raghava KS, Poongodi R, Darshan HN

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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Indian Journal of Obstetrics and Gynecology 12(2):p 91-94, April - June 2024. | DOI: http://dx.doi.org/10.21088/ijog.2321.1636.12224.7

How Cite This Article:

Purini PY, Sharmila V, Raghava KS, et al. Recent updates on carcinosarcoma of the uterus. Indian J Obstet Gynecol. 2024;12(2):91-4.

Timeline

Received : May 05, 2024         Accepted : June 20, 2024          Published : June 29, 2024

Abstract

Carcinosarcoma is a very rare, aggressive malignant neoplasm of the uterus and it is associated with poor prognosis. We are presenting a case of a 66-year-old multiparous postmenopausal women who had bleeding for a period of 3 months. On MRI Imaging there is a 6 cm lesion in the endometrial cavity, biopsy from the endometrium showed carcinosarcoma and she underwent extrafascial hysterectomy with bilateral slapingoophorectomy, omentectomy, and retroperitoneal lymph node dissection. Postoperatively ascites is positive for malignant cells, histopathology of specimen reported as carcinosarcoma FIGO grade 3 and lymph nodes are positive for malignancy. She received adjuvant chemotherapy with carboplatin and paclitaxel.

References

  • 1.   Anupama R, Kuriakose S, Vijaykumar DK, Pavithran K, Jojo A, Indu RN, Sheejamol VS. Carcinosarcoma of the uterus-a single institution retrospective analysis of the management and outcome and a brief review of literature. Indian J Surg Oncol. 2013 Sep;4(3): 222-8. doi: 10.1007/s13193-012-0206-7. Epub 2013 Jan 27. PMID: 24426726; PMCID: PMC3771046.
  • 2.   Adachi, Y., Nonogaki, H., Minamiguchi, S., Li, M., & Ikehara, S. (2016). Carcinosarcoma of the uterus: A case report. Molecular and Clinical Oncology, 4, 571-573. https://doi.org/10.3892/mco.2016.744.
  • 3.   McCluggage WG. Malignant biphasic uterine tumours: carcinosarcomas or metaplastic carcinomas? J Clin Pathol. 2002 May;55(5):321-5. doi: 10.1136/jcp.55.5.321. PMID: 11986333; PMCID: PMC1769650.
  • 4.   Menczer J. Review of Recommended Treatment of Uterine Carcinosarcoma. Curr Treat Options Oncol. 2015 Nov;16(11):53. doi: 10.1007/s11864-015-0370-4. PMID: 26374341.
  • 5.   Jaime Prat, ‘Nomonde Mbatani Uterine sarcomas. International Journal of Gynecology & Obstetrics pages: S105-S110 Volume 131Issue S2 First Published online: 11 October 30, 2018 https://doi. org/10.1002/ijgo.12613.
  • 6.   Bogani G, Ray-Coquard I, Concin N, et al. Int J Gynecol Cancer 2023;33:147–174.
  • 7.   Tuan HX, Duc NM, Tri CM, Quyen HD, Dung PX. Carcinosarcoma of uterus. Radiol Case Rep. 2023 Jan 15;18(3):1297-1301. doi: 10.1016/j.radcr.2022.12.070. PMID: 36684637; PMCID: PMC9851838.
  • 8.   Concin N, Planchamp F, Abu-Rustum NR, et al. European Society of Gynaecological Oncology quality indicators for the surgical treatment of endometrial carcinoma. Int J Gynecol Cancer 2021;31:1508–29.
  • 9.   Abu-Rustum NR, Yashar CM, Bradley K, et al. NCCN Guidelines® insights: uterine neoplasms, version 3.2021. J Natl Compr Canc Netw 2021;19:888–95.
  • 10.   Matsuzaki S, Klar M, Matsuzaki S, et al. Uterine carcinosarcoma: contemporary clinical summary, molecular updates, and future research opportunity. Gynecol Oncol 2021;160:586–601.
  • 11.   Raffone A, Travaglino A, Raimondo D, et al. Uterine carcinosarcoma vs endometrial serous and clear cell carcinoma: a systematic review and meta-analysis of survival. Int J Gynaecol Obstet 2022;158:520–7.
  • 12.   Travaglino A, Raffone A, Raimondo D, et al. Prognostic value of the TCGA molecular classification in uterine carcinosarcoma. Int J Gynaecol Obstet 2022;158:13–20.
  • 13.   Cancer Genome Atlas Research Network, Kandoth C, Schultz N, et al. Integrated genomic characterization of endometrial carcinoma. Nature 2013;497:67–73.

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This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

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This article does not involve any human or animal subjects, and therefore does not require ethics approval

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No conflicts of interest in this work.

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Cite this article

Purini PY, Sharmila V, Raghava KS, et al. Recent updates on carcinosarcoma of the uterus. Indian J Obstet Gynecol. 2024;12(2):91-4.

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator. 

Received Accepted Published
May 05, 2024 June 20, 2024 June 29, 2024
DOI: http://dx.doi.org/10.21088/ijog.2321.1636.12224.7

Keywords

Post menopausal bleedingPolypoidal massCarcinosarcomaMalignant mixed mullein tumour

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Timeline

Received May 05, 2024
Accepted June 20, 2024
Published June 29, 2024

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator. 


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