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Case Report

Primary Laryngeal Histoplasmosis

Keshav Gupta

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Journal of ENT and Allied Sciences 10(2):p 43-48, July - Dec. 2025. | DOI: https://doi.org/10.21088/rjeas.2456.5024.10225.1

How Cite This Article:

Keshav Gupta. Primary Laryngeal Histoplasmosis. RFP J ENT Allied Sci 2025; 10(2): 43–48

Timeline

Received : May 12, 2025         Accepted : June 02, 2025          Published : December 25, 2025

Abstract

Background: Histoplasma Capsulatum (HC) is a fungus known to infect the immunocompromised. It is present in bird droppings and soil. The fungus causes lung, eye and laryngeal infections in patients with poor immunity. Primary laryngeal histoplasmosis is a rare disease. Less than 100 cases have been recorded worldwide so far. Methods: A 68-year-old male with an undiagnosed laryngeal mass came with stridor. He was managed with emergency tracheostomy and repeat histopathological evaluation. This was confirmed as a case of primary laryngeal histoplasmosis. He improved withina few weeks with antifungal therapy. Discussion: The histopathological proof is necessary for its diagnosis. Once diagnosed, a few doses of the specific antifungal medicine do wonders. And that’s where we want your attention. Conclusion: A high degree of suspicion is required for its diagnosis. Treatment is quite simple. However, misdiagnosis and unnecessary interventions complicate its management.


References

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Keshav Gupta. Primary Laryngeal Histoplasmosis. RFP J ENT Allied Sci 2025; 10(2): 43–48


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
May 12, 2025 June 02, 2025 December 25, 2025

DOI: https://doi.org/10.21088/rjeas.2456.5024.10225.1

Keywords

Primary LaryngealHistoplasmosisHistoplasma Capsulatum

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Received May 12, 2025
Accepted June 02, 2025
Published December 25, 2025

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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