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Prevalence of Secondary Hyperparathyroidism in Patients with Stage 5 Chronic Kidney Disease on Maintenance Hemodialysis

Suresh U Kadli, Associate Professor, Department of General Surgery, Basaveshwara Medical College & Hospital, Chitradurga 577501, Karnataka, India. , Soumya NS1 , Suresh U Kadli2 , Kiran Kumd CK3 , Manjunath Rao SV4 , Sharath BV5 , Rahul Jain6

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Urology, Nephrology and Andrology International 6(2):p 61-65, July – December 2021. | DOI: http://dx.doi.org/10.21088/unai.2456-5016.6221.7

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Soumya NS, Suresh U Kadli, Kiran Kumd CK et. al/ Prevalence of Secondary Hyperparathyroidism in Patients with Stage 5 Chronic Kidney Disease on Maintenance Hemodialysis/Urology, Nephrology and
Andrology International./2021;6(2):61-65.
 

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Abstract

Context: Disturbances in mineral metabolism are commonly seen in patients with chronic renal failure.But there are very few studies on their prevalence in Indian dialysis population. Aim: To know the prevalence of secondary hyperparathyroidism in patients with stage 5 chronic kidney disease on maintenance hemodialysis. Settings and Design: Hospital based cross sectional study. Methods and Material: This study was done on 85 patients undergoing maintenance hemodialysis for ≥ six months and data was collected between January 2018 and December 2018, for a period of one year. Patients were examined for clinical features of secondary hyperparathyroidism and serum calcium, phosphorus, alkaline phosphatase, 25 hydroxy vitamin D and intact parathyroid hormone levels were measured. Statistical analysis used: The data was analysed with SPSS using Descriptive statistics, Chi-square testand significance by p value. Results: Various mineral, bone abnormalities in our study population were as follows-hypercalcemia (5.88%), hypocalcemia (36.47%), hyperphosphatemia (30.59%), hypophosphatemia (28.24%), hyperparathyroidism (36.48%), hypoparathyroidism (10.59%), deficiency of vitamin D(52.94%) and insufficiency of vitamin D (20%). Conclusions: Prevalence rate of secondary hyperparathyroidism was 36% in our study and 40% had oversuppresion of iPTH levels. One third of our patients had a risk of adynamic bone disease. Keywords: Chronic kidney disease; Secondary hyperparathyroidism; hemodialysis.

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Soumya NS, Suresh U Kadli, Kiran Kumd CK et. al/ Prevalence of Secondary Hyperparathyroidism in Patients with Stage 5 Chronic Kidney Disease on Maintenance Hemodialysis/Urology, Nephrology and
Andrology International./2021;6(2):61-65.
 

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DOI: http://dx.doi.org/10.21088/unai.2456-5016.6221.7

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