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Pcos in Adolescent Girls: Pathophysiology and Clinical Features

Alka Patil, Professor & Head, Dept. of Obstetrics and Gynaecology, ACPM Medical College, Dhule, Maharashtra 424002, India. , Alka Patil* , Amol Koranne** , Rahul V Patil***

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Indian Journal of Trauma and Emergency Pediatrics 10(1):p 17-23, January - March 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijtep.2348.9987.10118.3

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Abstract

The Polycystic Ovarian Syndrome is a complex condition in women associated with psychological, reproductive & metabolic features. The syndrome is diagnosed when following three criteria are present:

1. Anovulation/ Oligo ovulation. 2. Biochemical hyperandrogenism. 3. Polycystic ovaries observed ultrasonographycally. Clinical and biochemical features of PCOS can arise due to excess androgen secretion by ovary due to LH secretion from genetically programmed HP unit long before puberty likely during intrauterine life. Puberty triggers PCOS in predisposed girls. Syndrome is result of interaction of genetic and environmental factors. Diagnosis of PCOS in adolescent girls is based on abnormal uterine bleeding pattern and evidence of hyperandrogenism. PCOS is known to be associated with reproductive morbidity and increased risk of endometrial cancer. Diagnosis is important because of increased metabolic and and cardiovascular risk.

Keywords: Polycystic Ovarian Syndrome; Adolescence; Hyperandrogenism; Insulin Resistance Anovulation. 

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DOI: DOI: http://dx.doi.org/10.21088/ijtep.2348.9987.10118.3

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