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International Physiology 2(1):p 25-27, January - June 2014. | DOI:
Review Article
Mitochondrial Function and Dysfunction in Diabetic Peripheral Neuropathy: An Updated Overview of Studies to Implicate Physiological Basis of Neuropathological Condition
Nisha Rani Jamwal , Nisha Rani Jamwal , Kumar Senthil P. , Kumar Anup , Adhikari Prabha , Jeganathan PS , D’Souza Mariella
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International Physiology 2(1):p 25-27, January - June 2014. | DOI:
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Abstract
This short communication article was aimed to provide an evidence-informed overview and a scoping review of the role of mitochondrial function/dysfunction in diabetic peripheral neuropathy (DPN). From the reviewed studies, it is apparently evident that mitochondria played a comprehensive role not only in predisposing oxidative stress but also in programmed cell death or apoptosis in DPN.
Keywords: Mitochondrial function; Oxidative stress; Pathophysiology; Diabetic neuropathy.
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