Full Text (PDF)
Case Report

Management of Dentinogenesis Imperfecta by Prosthodontic Approach: A Case Report

Gibi Babu Philip null, Anas Khan1 null, Gibi Babu Philip2 null, Ann Mary Varghese3 null, Lakshmi Mohan null

Author Information

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Indian Journal of Forensic Odontology 17 (2):p 79-82, July - Dec 2024. | DOI: https://doi.org/10.21088/ijfo.0974.505X.17124.5

How Cite This Article:

Anas Khan, Gibi Babu Philip, Ann Mary Varghese et al. Management of Dentinogenesis Imperfecta by Prosthodontic Approach A Case Report. Ind J Forensic Odontol 2024;17(1):79-82.

Timeline

Received : September 30, 2024         Accepted : November 07, 2024          Published : December 25, 2024

Abstract

Dentinogenesis imperfecta (DI) is a genetic disorder affecting the developmental integrity of the dentin which results in weakened dentin. It is inherited as an autosomal dominant trait. The affected teeth, generally the posterior teeth will have to be extracted due to severity in wear and thereby possible fracture. This commonlyresults in loss of posterior occlusion and reduced vertical dimension. Apart from wear and fracture, anterior teeth may have an unesthetic appearance because of discoloration. Early diagnosis and treatment of DI is recommended, as it may prevent or intercept deterioration of the teeth and its occlusion. This article presents a case report of Prosthodontic Management of a patient diagnosed with Dentinogenesis Imperfecta.
 


References

  • 1.   Witkop CJ Jr. Manifestations of genetic diseases in the human pulp. Oral Surg Oral Med Oral Pathol. 1971;32:278–316.
  • 2.   Pettiette MT, Wright JT, Trope M. Dentinogenesis imper- fecta: endodontic implications. Case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;86:733–737.
  • 3.   Prockop DJ, Kivirikko KI. Heritable diseases of collagen. NEngl J Med. 1984;311:376–386.
  • 4.   Malmgren B, Lindskog S, Elgadi A, Norgren S. Clinical, histopathologic, and genetic investigation in two large families with dentinogenesis imperfecta type II. Hum Genet. 2004;114:491– 498.
  • 5.   Rajpar MH, Koch MJ, Davies RM, Mellody KT, Kielty CM, Dixon MJ. Mutation of the signal peptide region of the bicistronic gene DSPP affects translocation to the endoplasmic reticulum and results in defective dentinebiomineralization.HumMol Genet. 2002;11:2559–2565.
  • 6.   Dong J, Gu T, Jeffords L, MacDougall M. Dentin phosphoprotein compound mutation in dentin sialophosphoprotein causes dentinogenesis imperfecta type III. Am J Med Genet A. 2005;132A: 305–309.
  • 7.   Waltimo J, Ranta H, Lukinmaa PL. Ultrastructure of dentin matrix in heritable dentin defects. Scanning Microsc. 1995;9:185–97.
  • 8.   Modesto A, Alves AC, Vieira AR, Portella W. Dentinogenesis imperfecta type II: case report. Braz Dent J. 1996:7.47–52
  • 9.   Bouvier D, Duprez JP, Morrier JJ, BoisD.Strategies for rehabilitation in the treatment of dentinogenesis imperfecta in a child: a clinical report. J Prosthet Dent. 1996;75:238–241.
  • 10.   Henke DA, Fridrich TA, Aquilino SA. Occlusal rehabilitation of a patient with dentinogenesis imperfecta: a clinical report. J Prosthet Dent. 1999;81:503–506

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


About this article


Cite this article

Anas Khan, Gibi Babu Philip, Ann Mary Varghese et al. Management of Dentinogenesis Imperfecta by Prosthodontic Approach A Case Report. Ind J Forensic Odontol 2024;17(1):79-82.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
September 30, 2024 November 07, 2024 December 25, 2024

DOI: https://doi.org/10.21088/ijfo.0974.505X.17124.5

Keywords

Dentinigenous ImperfectaProsthodonticsManagement.ProsthodonticsManagement.

Article Level Metrics

Last Updated

Saturday 17 October 2026, 10:47:01 (IST)


1937

Accesses

20
267
00

Citations


NA
NA
NA

Download citation


Article Keywords


Keyword Highlighting

Highlight selected keywords in the article text.


Timeline


Received September 30, 2024
Accepted November 07, 2024
Published December 25, 2024

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Access this article



Share