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Indian Journal of Anesthesia and Analgesia 10(3):p 119-122, July-September 2023. | DOI: 10.21088/ijaa.2349.8471.10323.5
Case Report
Hypokalemic Periodic Paralysis: A Case Report
Naga Seshu Kumari Vasantha, Sonnappa Marappax Kushal1, Ankitha Sunand, Ravi Madhusudhana
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Anesthesia and Analgesia 10(3):p 119-122, July-September 2023. | DOI: 10.21088/ijaa.2349.8471.10323.5
How Cite This Article:
Sonnappa Marappa Kushal, Ankitha Sunand, Naga Seshu Kumari Vasantha, et al./Hypokalemic Periodic Paralysis: A Case Report/Indian J Anesth Analg. 2023;10(3) 119-122.Timeline
Received : August 08, 2023
Accepted : July 31, 2023
Published : August 30, 2023
Abstract
Introduction: Hypokalemic Periodic Paralysis is one form of Periodic Paralysis, a rare group of disorders that can cause sudden onset weakness. Although rare, Periodic paralysis must be differentiated from other causes of weakness and paralysis so that the proper treatment can be initiated quickly.
Case Report: A 72 year-old elderly male presented to the emergency room with sudden onset of paralysis. He had no respiratory or swallowing difficulty and was able to move his neck and facial muscles.
Neurologic exam revealed flaccid paralysis bilateral lower extremities which involved the proximal and distal muscles. Sensation was intact but deep tendon reflexes were slightly diminished to 3 out of 4 throughout. RFT deranged with serum creatinine level of 1.7 (0.6- 1.2mg/dl), potassium level of 1.6 (3.5–5 mmol/L), magnesium level of 0.9 (1.3-2.1meq/l).
Electrocardiogram revealed bradycardia and left axis deviation. Two hours after initiation of intravenous potassium replacement, the patient's neurologic symptoms started resolving.
The patient was diagnosed with Hypokalemic Periodic Paralysis and was started on calcium channel blocker for control of blood pressure. He was discharged home with an appointment to follow up.
Conclusion: Periodic Paralysis should be kept in mind when a patient comes with sudden onset weakness or paralysis, especially when other diseases have been ruled out. It can be life threatening if the treatment is improper, but intervention and subsequent correction of potassium abnormalities can clear the symptoms completely. The underlying etiology should be searched properly to avoid recurrence or persistence of the paralysis.
References
- 1. Jurkat-Rott K, Lerche H, Lehmann-Horn F. Skeletal muscle channelopathies. J Neurol. 2002;249(11):1493-502.
- 2. Lin SH, Lin YF, Chen DT, Chu P, Hsu CW, Halperin ML. Laboratory tests to determine the cause of hypokalemia and paralysis. Arch Intern Med. 2004;164(14):1561-6.
- 3. Kelley DE, Gharib H, Kennedy FP, Duda RJ Jr, McManis PG. Thyrotoxic periodic paralysis. Report of 10 cases and review of electromyographic findings. Arch Intern Med. 1989;149(11):2597-600.
- 4. Note: The extraneous text (
- 5. Fontaine B, Vale-Santos J, Jurkat-Rott K, Reboul J, Plassart E, Rime CS, Elbaz A, Heine R, Guimaraes J, Weissenbach J, et al. Mapping of the hypokalaemic periodic paralysis (HypoPP) locus to chromosome 1q31-32 in three European families. Nat Genet. 1994;6(3):267-72.
- 6. Wang W, Jiang L, Ye L, Zhu N, Su T, Guan L, Li X, Ning G. Mutation screening in Chinese hypokalemic periodic paralysis patients. Mol Genet Metab. 2006;87(4):359-63.
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Cite this article
Sonnappa Marappa Kushal, Ankitha Sunand, Naga Seshu Kumari Vasantha, et al./Hypokalemic Periodic Paralysis: A Case Report/Indian J Anesth Analg. 2023;10(3) 119-122.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| August 08, 2023 | July 31, 2023 | August 30, 2023 |
DOI: 10.21088/ijaa.2349.8471.10323.5
Keywords
Familial Hyperkalemic ParalysisHypokalemic Periodic ParalysisThyrotoxic Periodic ParalysisSearch for Similar Articles
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Timeline
| Received | August 08, 2023 |
| Accepted | July 31, 2023 |
| Published | August 30, 2023 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
