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Ganglion Impar Chemical Neurolysis in Advanced Carcinoma Prostate

Firoz Khan N, Navita Purohit

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Indian Journal of Anesthesia and Analgesia 10(1):p 23-26, January-March 2023. | DOI: 10.21088/ijaa.2349.8471.10123.3

How Cite This Article:

Firoz Khan N, Navita Purohit/Ganglion Impar Chemical Neurolysis in Advanced Carcinoma Prostate/Indian J Anesth Analg. 2023;10(1)23-26.  

Timeline

Received : December 26, 2022         Accepted : January 03, 2023          Published : February 09, 2023

Abstract

Ganglion impar is a solitary ganglion located retroperitoneally at the end of para vertebral sympathetic chain and usually in front of sacrococcygeal joint. Solitary or metastatic tumour in the surrounding tissues causes poorly localized pain. This is a case of 76 year old male, who was diagnosed to have advanced metastatic adenocarcinoma prostate, presented with pain over the lower back radiating to ano rectal region since last 4 months. He had severe pain during defecation which could not be controlled with conventional high-dose opioid application but with transcoccygeal Ganglionimpar chemical neurolysis. We reasoned that blocking the ganglion impar could attenuate this sympathetically maintained pain, which would lead to a reduction in the consumption of opioids, lessen constipation, and lead to an improvement in the patient’s quality of life.


References

  • 1.   Agarwal-Kozlowski K, Lorke DE, Habermann CR, Am Esch J, Beck H. CT-guided blocks and neuroablation of the ganglion impar (Walther) in perineal pain. Anatomy, technique, safety and efficacy. Clin J Pain. 2009;25(7):570–6.
  • 2.   Christo PJ, Mazloomdoost D. Interventional pain treatments for cancer pain. Ann N Y Acad Sci. 2008;1138:299–328.
  • 3.   Do NL, Nagle D, Poylin VY. Radiation proctitis: Current strategies in management. Gastroenterol Res Pract. 2011;2011:917941.
  • 4.   Eker HE, Cok OY, Kocum A, Acil M, Turkoz A. Transsacrococcygeal approach to ganglion impar for pelvic cancer pain: A report of 3 cases. Reg Anesth Pain Med. 2008;33(4):381–2.
  • 5.   Bas¸ ag˘ an Mog˘ ol E, Türker G, Kelebek Girgin N, Uçkunkaya N, Sahin S. Blockade of ganglion imparm through sacrococcygeal junction for cancer-related pelvic pain. Agri. 2004;16(4):48–53.
  • 6.   Kuthuru M, Kabbara AI, Oldenburg P, Rosenberg SK. Coccygeal pain relief after transsacrococcygeal block of the ganglion impar under fluoroscopy: A case report. Arch Phys Med Rehabil. 2003;84(11):E24.
  • 7.   Toshniwal GR, Dureja GP, Prashanth SM. Transsacrococcygeal approach to ganglion impar block for management of chronic perineal pain: A prospective observational study. Pain Physician. 2007;10(5):661–6.
  • 8.   Waldman SD. Ganglion of Walther (Impar) Block: Trans-Coccygeal Technique. In: Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC, editors. Atlas of Interventional Pain Management. 3rd ed. Philadelphia (PA): Saunders Elsevier; 2009. p. 483–90.
  • 9.   Plancarte R, Velazquez R, Patt RB. Neurolytic blocks of the sympathetic axis. In: Patt RB, editor. Cancer Pain. Philadelphia (PA): Lippincott-Raven; 1993. p. 419–42.
  • 10.   Munir MA, Zhang J, Ahmad M. A modified needle in needle technique for the ganglion impar block. Can J Anaesth. 2004;51(9):915–7.
  • 11.   Pereira PL, Günaydin I, Duda SH, Gaa J, Tatsch K, Huppert P. Corticosteroid injections of the sacroiliac joint during magnetic resonance: Preliminary results. J Radiol. 2000;81(3):223–6.
  • 12.   Benzon HT, Hurley RW, Deer T. Chronic pain management. In: Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC, editors. Clinical Anesthesia. 6th ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2009. p. 1506–19.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Firoz Khan N, Navita Purohit/Ganglion Impar Chemical Neurolysis in Advanced Carcinoma Prostate/Indian J Anesth Analg. 2023;10(1)23-26.  


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
December 26, 2022 January 03, 2023 February 09, 2023

DOI: 10.21088/ijaa.2349.8471.10123.3

Keywords

Carcinoma prostateGanglion imparPhenolChemical NeurolysisFluoroscopic

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Received December 26, 2022
Accepted January 03, 2023
Published February 09, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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