Abstract

Escitalopram is the therapeutically active S-enantiomer of RS-citalopram, a commonly prescribed SSRI. The R-enantiomer is essentially pharmacologically inactive. Escitalopram is used for the treatment for major depressive disorder (MMD) and also an anxiety disorder. It is a selective serotonin reuptake inhibitor (SSRI). The drug enhances the activity of serotonin in the central nerves system. It has high selective inhibitor of serotonin and transporter protein. It process the rapid onset of the antidepressant and it effective and generally well tolerated treatment for MMD disorder. Significant difference can be seen between escitalopram and placebo and changes in the scores after 24 weeks of treatment. In this review paper, the HPTLC, is a simple, rapid, and accurate technique. This method is used to established and validated for simultaneous analysis of the escitalopram oxalate.

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