Heading
Description: Pathogenesis of fat embolism. Three thenries have been proposed: mechanical, coagulation, and biochemical. Fat embolisation causes local parenchymal damage after vascular occlusion (by fat or thrombus), an exaggerated inflammatory response, or both. Subsequently, pulmonary haemorrhage, consolidation, pulmonary oedema and/or alveolar collapse result in a ventilation (V)/ perfusion (Q) mismatch and hypoxaemia. CRP, C-reactive protein
