Home > Journals > Indian Journal of Biology

Indian Journal of Biology

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Correlation of Various Clinico-Pathological Parameters with Estrogen Receptor and Progesterone Receptor Status in Malignant Breast Lesions

Mohanty Swati Sucharita* , Mohanty Swati Sucharita* , Mohanty Prafulla Kumar** , Mohanty Sumit Subhadarshi*** , Thakur Padmalaya**** , Surabhi*****

Author Information

Licence:



Indian Journal of Biology 2(1):p 67-71, Jan-Jun 2015. | DOI: DOI: https://dx.doi.org/10.21088/ijb.2394.1391.2115.11

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Breast carcinoma is emerging as the common most malignancy globally. In India, the rate of cervix cancer is decreasing while breast cancer is on the increase, especially in urban areas. Breast carcinoma continues to be a major health problem despite a decrease in mortality rate over the past 2 decades. The aim of this study is to determine if any correlation exists between estrogen receptor (ER) and progesterone receptor (PR) with respect to age, menopausal status, grade, tumor size and lymph node status in breast carcinoma. A total 50 cases of invasive duct cancers were included in this study. This study was on histopathology of excised specimens of 50 females with breast carcinoma operated by trained doctors. The hormone receptors were assessed immunohistochemically and compared with patient’s age, menopausal status, grade, tumor size and lymph node status of tumor. Correlating the above factors with hormone receptor status, increase positivity of ER/PR in post menopausal age group (66.67%), small tumor size (83.33%), moderately differentiated tumors (76.67%) and negative lymph node status (56.67%) was found. Assessment of hormone receptors for clinical management of breast cancer patients is strongly advocated to provide prognostic information and better therapeutic options.

Keywords: Breast Carcinoma; Estrogen; Progesterone. 

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: DOI: https://dx.doi.org/10.21088/ijb.2394.1391.2115.11

Keywords


Article Level Metrics

Last Updated

Monday 22 June 2026, 07:32:40 (IST)

659

Accesses

2
224
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share