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Comparative Study of Intravenous Iron Sucrose Versus Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia during Pregnancy and Postpartum Period

Nitin N. Kulkarni, Associate Professor, Department of Obstetrics and Gynaecology, ACPM Medical College, Dhule, Maharashtra 424002, India. , Nitin Kulkarni1 , Pankaj Pawar2 , Radhika Bansal3

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Indian Journal of Maternal-Fetal & Neonatal Medicine 5(1):p 32-35, January - June 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.5118.6

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Abstract

Objectives: The present study aims at advantages of ferric carboxymaltose therapy over iron sucrose in iron deficiency anaemia of ante natal and postnatal patient.

Methods: A prospective observational study was carried out at ACPM medical college during January 2017 to December 2017 for 50 antenatal and 50 postnatal women, total 100 women. Diagnosis of iron deficiency anemia done by proper history taking, examination, peripheral blood smear and blood indices. Baseline haemoglobin and serum ferritin levels were noted on first, eighth, fifteenth and thirtieth day of treatment with iron sucrose or ferric carboxymaltose for randomly selected 50 antenatal and 50 postnatal women.

Results: The mean rise of haemoglobin value was 4.3 g/ L for ferric carboxymaltose and 4.0 g/L for iron sucrose in pregnant women. For postpartum women mean rise of haemoglobin was 4.9 g/L after treatment with ferric carboxymaltose and 4.4 g/L for iron sucrose.

Conclusion: For the treatment of iron deficiency anaemia in pregnancy as well as postnatal women ferric carboxymaltose is safe, efficient and having many advantages over iron sucrose.

Keywords: Iron deficiency anaemia; Iron sucrose; Iron ferric carboxymaltose 


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DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.5118.6

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