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Case Report

Clozapine-Induced Diabetic Ketoacidosis: A Case Report

Ankush Sharma , Syed Mohsin Ishaq1 , Ankush Sharma2 , Vinay Gupta3 , Fleming Mathew4 , Mawra5 , Seher Kirmani6

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Indian Journal of Communicable Diseases 6(2):p 63-65, JULY- DECEMBER 2020. | DOI: http://dx.doi.org/10.21088/ijcd.2395.6631.6220.10

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Syed Mohsin Ishaq, Ankush Sharma, Vinay Gupta, et al., Clozapine-Induced Diabetic Ketoacidosis: A Case Report. Indian
J Comm Dis 2020;6(2):63–65.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Atypical antipsychotics are of great benefit to patients suffering from psychiatric disorders, such as bipolar disorder and schizophrenia. Yet they have a wide array of adverse effects including metabolic disturbances. One such rare but potentially fatal complication is Diabetic ketoacidosis, associated with the use of Clozapine, an atypical antipsychotic. The objective of this article is to report a case of a 35-year-old male with underlying schizophrenia on clozapine 200mg BD who presented in the emergency with complaints of abdominal discomfort, sweating, vomiting and palpitations. The patient was managed as a case of diabetic ketoacidosis(DKA). Thorough investigations ruled out other possible causes. This study outlines the importance of being vigilant while managing a case with psychiatric disorder being treated with clozapine as the drug can lead to new-onset diabetes and diabetic ketoacidosis. Patients on clozapine must be regularly monitored especially during the early course of treatment to avoid the onset of such fatal adverse effects.
Keywords: Diabetic Ketoacidosis; Clozapine-Induced.

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Cite this article

Syed Mohsin Ishaq, Ankush Sharma, Vinay Gupta, et al., Clozapine-Induced Diabetic Ketoacidosis: A Case Report. Indian
J Comm Dis 2020;6(2):63–65.
 

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DOI: http://dx.doi.org/10.21088/ijcd.2395.6631.6220.10

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