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Clinico: Pathological Study of Diffuse Axonal Injury and Outcome Analysis

K. Ravi , Gudla Venugopal1 , K. Ravi2 , N. Panduranga Rao3 , M. Premjit Ray4

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International Journal of Neurology and Neurosurgery 11(1):p 24-29, January-March 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.11119.4

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Abstract

 Background: DAI is considered the most important factor in determining morbidity and mortality in victims of TBI and is the most common cause of posttraumatic coma, disability, and a persistent neurovegetative state. Aim: To predict the outcome with GCS at admission and CT Scan and MRI findings. Materials and methods: It was a prospective cohort study in a group of 59 patients with head injury cases with GCS < 12. All the head injury cases with normal CT scan and > 6 hrs were taken in study. Mode of injury, incidence among various age groups, sex distribution, post resuscitative Glasgow Coma Scale were noted in patients. Mortality and morbidity analysed with respect to GCS and CT & MRI Scan findings. Results: DAI constitutes 1.72% of total head injury admissions & 20.06% in severe head injury. MRI is more sensitive compared to CT. Mortality in our series is 32.20%. Most of DAI are due to road traffic accidents. Second and third decade populations are more in DAI. Neurological deficits improved almost completely (over the 1½ years to 2 years) and early recovery seen in younger age groups compared to elder age groups. In 27.5% of cases recovery is good as per GCS. Conclusion: In Patients with diffuse axonal injury the help of GCS, CT Scan and MRI findings one can know which patients can be salvaged. Keywords: Diffuse Axonal Injury (DAI).


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DOI: DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.11119.4

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