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Indian Journal of Maternal-Fetal & Neonatal Medicine

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Clinico-Pathological Correlation of Ovarian Malignancies

Ankita Sanjay Gharge , Savita Ashutosh Somalwar1 , Ankita Sanjay Gharge2 , Anjali Shirish Kawthalkar3 , Nikita Vijay4

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Indian Journal of Maternal-Fetal & Neonatal Medicine 6(1):p 33-38, Jan-June 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.6119.7

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Abstract

Context: Ovarian malignancy is a clinical entity that is diagnosed late, that is in an advanced stage of the disease. The present study highlights the correlation between the clinical and pathological features of neoplastic lesions of ovary in order to arrive at a better understanding of the disease process. The objective of study is to assess the overall incidence of various histological types of ovarian neoplasm, the pattern of occurrence of ovarian tumors in relation to age, parity and modes of presentations and to study the histopathological findings of various ovarian tumors. Aims: To study frequency and clinical presentation of ovarian malignancies and to correlate the clinical presentation of ovarian malignancies with the histopathological findings. Setting and Design: This cross sectional study was carried out at a tertiary care center catering both rural and urban population. Materials and Methods: Cases diagnosed with ovarian malignancy over a period of 4 years from April 2014 to March 2018 were included. Data was collected from the indoor files at the time of discharge. Data included detailed history of the women including history of presenting complaints, family history of malignancy, duration of symptoms to reporting to hospital, menstrual history and obstetric history. Relevant investigations like tumor markers level (CA125, inhibin, beta HCG, alpha fetoprotein, Alkaline phosphates) and USG findings were noted and CT scan reports were noted. Correlation of clinical diagnosis with histopathology was done. Statistical Analysis used: Statistical analysis was done as percentages of selected subjects and application of p value and Chi square test (wherever applicable).

Keywords: Ovarian Malignancy; Neoadjuvant chemotherapy; Tumor Marker; Histopathology.

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DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.6119.7

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