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Clinical Profile of Patients with Guillain-Barre Syndrome (GBS)

Naveen Thota, Associate Professor, Department of Neurology, Sri Venkateswara Institute of Medical Sciences, Tirupathi, Andhra Pradesh 517507, India. , Naveen Prasad S.V.1 , Naveen Thota2 , Anil Kumar K.3 , Vengamma B.4

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International Journal of Neurology and Neurosurgery 10(3):p 264-268, Jul-Sep 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.10318.19

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Abstract

  Antecedent infection with following organism likecytomegalovirus, Epstein Barr virus, Varicella zoster virus, Human immunodeficiency virus (HIV), Campylobacter jejuni, Mycoplasma pnemoniae and Shigella are implicated in the causation of the Guillain Barre Syndrome. In all the patients the following data were recorded: demographic data; season in which patient developed disease; detailed history of present and preceding (if any) illness; physical as well as neurological examination details; laboratory characteristics including CSF analysis (if done); electrophysiological findings, any need for assisted mechanical ventilation, duration of mechanical ventilation; duration of hospital stay; any complications; treatment given and outcome. The median duration to get admitted in hospital from disease onset was 8 (range 4­18) days, and the median time to reach nadir of the disease was 7 (range 5­14) days. The median duration of total hospital stay was 16 days, with minimum and maximum duration of hospital stay being 7 and 60 days, respectively. All patients presented with symmetrical weakness. Quadriparesis was present in 54 (88.5%) patients.
Global areflexia was present in 53 (88.6%) patients.

Keywords: Guillain­Barre Syndrome; Epstein Barr Virus; Clinical Profile.

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DOI: DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.10318.19

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