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Indian Journal of Maternal-Fetal & Neonatal Medicine 4(1):p 37-42, January - June 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.4117.6
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Bacteriological Profile and Antibiogram of Neonatal Sepsis in a Tertiary Care Hospital
Londhe A.C.* , Londhe A.C.* , Deshmukh L.S.** , Joshi A.K.***
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Indian Journal of Maternal-Fetal & Neonatal Medicine 4(1):p 37-42, January - June 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.4117.6
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Abstract
Introduction: Neonatal sepsis is one of the major causes of neonatal morbidity and mortality. It is responsible for about 30-50% of the total neonatal deaths in developing countries. Delay in diagnosis and treatment of sepsis can have devastating consequences in a neonate. So, surveillance is necessary to identify common signs and the bacterial pathogen as well as its antibiotic sensitivity pattern in a particular area. Methodology: This was a retrospective study conducted in Government Medical College and Hospital, Aurangabad from October 2013 to September 2015. Data was collected retrospectively by analyzing case sheet papers of neonates admitted to Neonatal Intensive Care Unit (NICU), GMCH Aurangabad during the study period. Results: Out of 3217 babies admitted to NICU, 523 (16%) developed culture positive sepsis. Females and preterm babies were more affected. Gram negative isolates were more common with Enterobacter aerogens being the most common organism followed by Klebsiella pneumoniae. Staphylococcus aureus was the most common gram positive isolate. There was wide spread resistance to cephalosporins among gram negative organisms. Conclusion: Early onset sepsis was more common in our set up. Gram negative organisms were predominant. Enterobacter aerogens was the most common isolate followed by Klebsiella pneumoniae. All gram negative organisms were resistant to cephalosporins. Staphylococcus aureus was most common gram positive isolate.
Keywords: Neonate; Sepsis; Culture; Antibiotic Sensitivity
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DOI: DOI: http://dx.doi.org/10.21088/ijmfnm.2347.999X.4117.6
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