Abstract

Phytochemicals derived from various herbs hold a promise in treating the oxidative stress in various diseases. The aim of this study was to measure the antioxidant activity of various extracts prepared from the bark and leaves of Anthocephalus cadamba (Roxb.) Mique (Rubiaceae) plant. The Ferric reducing ability of plasma (FRAP, also Ferric ion reducing antioxidant power) assay was used to assess the oxidative potential of various extracts. The results show that methanol extracts of the bark and the leaves give the higher TAC FRAP values. The results obtained have the potential of bark and leaf extracts of A. cadamba to be exploited pharmacologically in future.
 

• 1.   Anonymous. The Wealth of India. Vol. I. New Delhi: CSIR; 1985. p. 305-307.
• 2.   Bagchi K, Puri S. Free radicals and antioxidants in health and disease. East Mediterr Health J. 1998;14:350-360.
• 3.   Benzie IF, Strain JJ. Ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: the FRAP assay. Anal Biochem. 1996;239:70-76.
• 4.   Bhandary MJ, Chandrashekhar KR, Kaveriapa KM. Medical ethnobotany of the Siddis of Uttara Kannada district, Karnataka. J Ethnopharmacol. 1998;47:149-158.
• 5.   Gupta SS. Prospects and perspectives of natural plant products in medicine. Indian J Pharmacol. 1994;26:1-12.
• 6.   Kapil A, Koul IB, Suri OP. Antihepatotoxic effects of chlorogenic acid from Anthocephalus cadamba. Phytother Res. 1995;9:189-193.
• 7.   Majumdar A. Home remedies in Ayurveda. 1st ed. New Delhi: Amargranth Publication; 2002. p. 296-297.
• 8.   Naithani HB, Sahni KC. Forest Flora of Goa. Dehradun (India): International Books Distributors; 1997. p. 318.
• 9.   Pal DC, Jain SK. Tribal Medicine. New Delhi: Naya Prakash; 2000. p. 246-247.
• 10.   Rastogi RP, Mehrotra BN. Compendium of Indian Medicinal Plants. Vol. 3. New Delhi: CSIR; 1993. p. 49.
• 11.   Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationship of flavonoids and phenolic acids. Free Radic Biol Med. 1996;20:933-956.
• 12.   Sahu PN, Koike K, Zhonghua J, Banarjee S, Mondal NB, Nikaido T. Triterpene glycosides from the bark of Anthocephalus cadamba. J Chem Res. 2000;1:22-23.
• 13.   Salkar IV, Kakkar KK, Chakre OJ. Glossary of Indian Medicinal Plants with Active Principles. Part I. New Delhi: CSIR; 1992. p. 75.
• 14.   Sung H, Nah J, Chun S, Park H, Yang SE, Min WK. In vivo antioxidant effect of green tea. Eur J Clin Nutr. 2000;54:527-529.