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Case Report

Acetaminophen Ingestion Turns Toxic

Bhumika Rajpal, Manas Mitra, Arun Kaushik, Kishalay Datta

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Indian Journal of Emergency Medicine 9(3):p 123-126, July-September 2023. | DOI: 10.21088/ijem.2395.311X.9323.14

How Cite This Article:

Rajpal B, Mitra M, Kaushik A, Nag A, Das I. Acetaminophen Ingestion Turns Toxic. Indian J Emerg Med. 2023;9(3):123–6.

Timeline

Received : April 12, 2023         Accepted : May 13, 2023          Published : June 09, 2023

Abstract

Acetaminophen, commonly called “Paracetamol” is an over the counter medication available in all the pharmacies in the Indian subcontinent. The emergency and critical care department is commonly involved in the diagnosis and treatment of acetaminophen poisoning patients. The treatment guidelines are ages old but in recent times, the presentation for acetaminophen poisoning has been varied. In this case report, we will discuss the diagnosis and management of acetaminophen poisoning in a child, along with review of literature.


References

  • 1.   Tan PC, Rajasingam G, Devi S, Kandasamy R, Jamil MA, Jamil A, et al. Dengue infection in pregnancy: prevalence, vertical transmission, and pregnancy outcome. Obstet Gynecol. 2008;111(5):1111–7.
  • 2.   Chansamouth V, Thammasack S, Phetsouvanh R, Keoluangkot V, Moore CE, Blacksell SD, et al. The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. PLoS Negl Trop Dis. 2016;10:e0004577.
  • 3.   Paixao ES, Teixeira MG, Costa Mda C, Rodrigues LC. Dengue during pregnancy and adverse fetal outcomes: a systematic review and meta-analysis. Lancet Infect Dis. 2016;16(7):857–65.
  • 4.   Pouliot SH, Xiong X, Harville E, Paz-Soldan V, Tomashek KM, Breart G, et al. Maternal dengue and pregnancy outcomes: a systematic review. Obstet Gynecol Surv. 2010;65(2):107–18.
  • 5.   Sharma S, Jain S, Rajaram S. Spectrum of Maternofetal Outcomes during Dengue Infection in Pregnancy: An Insight. Infect Dis Obstet Gynecol. 2016;2016:5046091.
  • 6.   Halstead SB. Pathogenesis of dengue: Challenges to molecular biology. Science. 1988;239(4844):476–81.
  • 7.   Arshad I, Malik FA, Hussain A, Shah SA. Dengue fever: Clinico-pathologic correlations and their association with poor outcome. Professional Med J. 2011;18(1):57–63.
  • 8.   American College of Obstetricians and Gynecologists: ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006: postpartum hemorrhage. Obstet Gynecol. 2006;108(4):1039–47.
  • 9.   World Health Organization (WHO)/TDR. Hand book for clinical management of dengue. Geneva, Switzerland: World Health Organization; 2012. p. 124.
  • 10.   Lye DC, Lee VJ, Sun Y, Leo YS, Wong J, Merchant AE, et al. Lack of efficacy of prophylactic platelet transfusion for severe thrombocytopenia in adults with acute uncomplicated dengue infection. Clin Infect Dis. 2009;48(9):1262–5.
  • 11.   De Azeredo EL, Monteiro RQ, de-Oliveira Pinto LM. Thrombocytopenia in Dengue: Interrelationship between Virus and the Imbalance between Coagulation and Fibrinolysis and Inflammatory Mediators. Mediators Inflamm. 2015;2015:313842.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

Information not provided.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Rajpal B, Mitra M, Kaushik A, Nag A, Das I. Acetaminophen Ingestion Turns Toxic. Indian J Emerg Med. 2023;9(3):123–6.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
April 12, 2023 May 13, 2023 June 09, 2023

DOI: 10.21088/ijem.2395.311X.9323.14

Keywords

Acetaminophen; Paracetamol poisoning; N-acetyl cysteine; Rumack Matthew nomogram.AcetaminophenParacetamol poisoningN-acetyl cysteineRumack Matthew nomogram

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Received April 12, 2023
Accepted May 13, 2023
Published June 09, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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