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A Study on Serum Uric Acid in Patients with Heart Failure

Abhilash K , Bhaskara1 , Abhilash K2 , Aishhwarrya Umeshchandra G3

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Indian Journal of Emergency Medicine 6(4):p 245-249, October- December 2020. | DOI: http://dx.doi.org/10.21088/ijem.2395.311X.6420.4

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Bhaskara, Abhilash K, Aishhwarrya Umeshchandra G. A Study on Serum Uric Acid in Patients with Heart Failure. Indian J
Emerg Med 2020;6(4):245–249.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Introduction: Elevated serum Uric Acid levels have been observed in clinical conditions associated with hypoxia. Cell death can cause accumulation of purine bodies and hence hyperuricemia. Increased activation of Xanthine Oxidase can be caused by tissue hypoxia, which itself is a consequence of vascular (and cardiac) dysfunction. Methodology: A detailed history was taken including past or current morbidities. A structured clinical examination and the laboratory investigation profile of the subjects was recorded on a predesigned proforma. Height was measured by a Stadiometer, weight was recorded using a spring based weighting scale. BMI was calculated using formula of BMI = Weight (in kg)/ Height (in metre2). Results: Serum Uric Acid level (SUA) estimation done in our study group of 85 patients diagnosed as congestive heart failure showed the following results – Patients with SUA <5 mg/dl consisted of 8.2% of the study group (n=7); patients with SUA 5.1–7 mg/dl consisted of 28.2% of the study group (n=24); the maximum number of patients had their SUA 7.1–9 mg/dl contributing 44.7% of the study group (n=38); whereas those with SUA >9 mg/dl contributed 18.8% of the group (n=16). Conclusion: Thus, a total of 49 patients (65.33%) had hyperuricemia. The mean SUA was 7.68 ± 2.26 mg/dl.
Keywords: Serum Uric Acid; Heart failure; Hyperuricemia.

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Cite this article

Bhaskara, Abhilash K, Aishhwarrya Umeshchandra G. A Study on Serum Uric Acid in Patients with Heart Failure. Indian J
Emerg Med 2020;6(4):245–249.
 

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DOI: http://dx.doi.org/10.21088/ijem.2395.311X.6420.4

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