Abstract

Multiple sclerosis is a chronic autoimmune inflammatory disease characterized by axonal degeneration and demyelination of the central nervous system Isolated facial nerve palsy is commonly seen with Bell's palsy. However, it can be associated with a central lesion at the level of the ipsilateral facial nucleus or the facial nerve at the pons. Isolated cranial neuropathies are rarely seen with multiple sclerosis. Isolated facial nerve palsy due to multiple sclerosis is a rare scenario and can often get misdiagnosed and treated as Bell's palsy. The patient being reported is a 30-year-old female who developed isolated facial nerve palsy, which was initially treated as Bell's palsy. However, she was found to be knowncase of multiple sclerosis.

• 1.   Calabresi PA. Diagnosis and management of multiple sclerosis. Am Fam Physician. 2004;70:1935–1944. [PubMed] [Google Scholar]
• 2.   Goldenberg MM. Multiple sclerosis review. P T. 2012;37:175–184. [PMC free article] [PubMed] [Google Scholar]
• 3.   Koch-Henriksen N, Sorensen PS. The changing demographic pattern of multiple sclerosis epidemiology. Lancet Neurol. 2010;9:520–532. [PubMed] [Google Scholar]
• 4.   Tullman MJ. Overview of the epidemiology, diagnosis, and disease progression associated with multiple sclerosis. Am J Manag Care. 2013;19(2 suppl):S15–S20. [PubMed] [Google Scholar]
• 5.   Kwon JY, Kim JY, Jeong JH, Park KD. Multiple sclerosis and peripheral multifocal demyelinating neuropathies occurring in a same patient. J Clin Neurol. 2008;4:51–57. [PMC free article] [PubMed] [Google Scholar]
• 6.   Gilden DH. Clinical practice. Bell's palsy. N Engl J Med. 2004;351:1323–1331. [PubMed] [Google Scholar]
• 7.   Tiemstra JD, Khatkhate N. Bell's palsy: diagnosis and management. Am Fam Physician 2007;76:997–1002. [PubMed] [Google Scholar]
• 8.   Gupta S, Mends F, Hagiwara M, Fatterpekar G, Roehm PC. Imaging the facial nerve: a contemporary review. Radiol Res Pract. 2013;2013:248039. [PMC free article] [PubMed] [Google Scholar]
• 9.   Critchley EP. Multiple sclerosis initially presenting as facial palsy. Aviat Space Environ Med. 2004;75:1001–1004. [PubMed] [Google Scholar]
• 10.   Fukazawa T, Moriwaka F, Hamada K, Hamada T, Tashiro K. Facial palsy in multiple sclerosis. J Neurol. 1997;244:631–633. [PubMed] [Google Scholar]
• 11.   Ivankovic M, Demarin V. From recurrent peripheral facial palsy to multiple sclerosis. ActaClin Croat. 2011;50:419–421. [PubMed] [Google Scholar]
• 12.   Bassetti C, Bogousslavsky J, Barth A, Regli F. Isolated infarcts of the pons. Neurology. 1996;46:165–175. [PubMed] [Google Scholar]
• 13.   Baugh RF, Basura GJ, Ishii LE, Schwartz SR, Drumheller CM, Burkholder R, et al. Clinical practice guideline: Bell's palsy. Otolaryngol Head Neck Surg. 2013;149(3 suppl):S1–S27. [PubMed] [Google Scholar]
• 14.   Misawa S, Kuwabara S, Mori M, Hayakawa S, Sawai S, Hattori T. Peripheral nerve demyelination in multiple sclerosis. ClinNeurophysiol. 2008;119:1829–1833. [PubMed]
• 15.   Uzawa A, Mori M, Ito S, Kuwabara S. Neurological picture. Isolated abducens and facial nerve palsies due to a facial collicular plaque in multiple sclerosis. J NeurolNeurosurg Psychiatry. 2011;82:85–86. [PubMed] [Google Scholar]
• 16.   Agarwal R, Manandhar L, Saluja P, Grandhi B. Pontine stroke presenting as isolated facial nerve palsy mimicking Bell's palsy: a case report. J Med Case Rep. 2011;5:287. [PMC free article] [PubMed] [Google Scholar]

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