Indian Journal of Pathology: Research and Practice

Unicystic ameloblastoma is a rare variant of ameloblastoma. We report a case of Unicystic ameloblastoma in a 29 year-old female with a pain and swelling in the left mandibular posterior region. Fine needle aspiration yielded no fluid. Periapical, panoramic and computer tomography scans showed well defined radiolucency present in relation to 36 and 37. Unicystic refers to those cystic lesions that show clinical, radiographic, or gross features of a cyst, but on histologic examination show a typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor growth. Enucleation and Tumor resection was performed for the treatment. Our case report is an attempt to help the dental community in developing familiarity with the clinical presentation and at the same time advocating to develop a high index of suspicion in recognizing such cases.

Keywords: Unicystic Ameloblastoma; Odontogenic tumor; Histopathology. 

Amyloidosis is a group of disorders characterized by the extra cellular deposition of a substance called amyloid in various tissues. When present as a conjunctival mass with recurrent haemorrhage the condition mimicks a neoplastic lesion. We report such a patient who had complaints of a conjunctival mass with recurrent subconjunctival haemorrhage. The diagnosis of amyloidosis was made by excisional biopsy and confirmed by Congo red staining. Further work up did not reveal any evidence of systemic amyloidosis. 

Key words : Conjunctival amyloidosis; Congo red; Neoplastic leison. 

Isolatedextra pulmonary tuberculous osteomyelitis of the phalanx is rare as compared to that of proximal bones. We report acase of tubercular osteomyelitis of the middle phalanx of the toe in a 74 year old lady, presenting as post traumatic chronic ulcer which is even morerare. The difficulty in diagnosis and the related problems, the need to have a high index of suspicion of tuberculosis as one of the causes of chronic foot ulcer especially in developing countries has been emphasized.

Key-words: Tuberculosis; Osteomyelitis; Phalanx; Toe. 

Involvement of urinary bladder has been documented in 10-25% of Lymphomas and Leukemias, but lymphoid neoplasms arising primarily in the urinary bladder are rare. Low grade B non-Hodgkin lymphomas are the most common. This is a case report of a 68-year old male with primary low-grade B non-Hodgkin Lymphoma of the urinary bladder consistent with extra-nodal Marginal zone lymphoma.

Keywords: Urinary Bladder; Low grade B NHL. 

Aim of Present Study, to show the immune status of Non-Hodgkin’s lymphoma patients we have cauterized again them according to stage wise also to study immune status (cellular as well as Hum oral) of these patients. Our studies reveal the status of patients which is help full for there treatment as well as there improvement status.

Key words: NHL (Non Hodgkin’s lymphoma); B cell (B lymphocyte); IgM (Immunoglobulin M); IgG (Immunoglobulin G); IgA (Immunoglobulin A); IgE (Immunoglobulin E); IgD (Immunoglobulin D).  

Tuberculosis is an oldest and common infectious disease. Detected as far back as 10,000 BC it still remains a major public health problem world wide The use of biological markers in the diagnosis of tuberculous pleural effusion (TPE) is a breakthrough Adenosine deaminase(ADA) has been proposed to be a useful surrogate marker for TB in pleural, peritoneal and pericardial fluids. Although sensitive it is not a specific diagnostic tool, but combined with other tests the sensitivity can be increased. Materials&methods; 100 patients of suspected TPE were studied .Sensitivity and specificity of pleural fluid ADA alone and in combination with Mantoux test, pleural fluid cytology studied. Conclusion; pleural fluid ADA (>63U/L) alone was essentially diagnostic of TPE, between 40-63U/L it is highly suspicious of TPE along with >50% lymphocytes in pleural fluid confirms the diagnosis.

Keywords: Tubercular pleural effusion; ADA; Mantoux test; Pleural fluid cytology.  

Introduction: Non haemolytic febrile transfusion reactions can be prevented by leucodepletion. In spite of effective leucodepletion, presence of platelet derived cytokines will limit the lifespan of platelets. Objective: To analyse the effect of pre storage leuco reduction by using clinical and laboratory parameters on packed cells and platelets. Materials and methods: 250 units of packed cells and 250 units of platelet concentrates which were prepared by TACE (quadruple bags were included for the study. Pre leucocyte count was done by automated cell counter and neubauer chamber. After separation of packed cells and platelets, post leukocyte count was done. As the number of cells was too low in platelet concentrate, Nagotte chamber was used for counting cells. After transfusion, occurrence of NHTFR was watched for and increment of haemoglobin was noted whenever possible. Results: The leucoreduction was in the range of 45% to 80% in packed cell preparation and 98-99.7% in platelet preparation. The reduction in platelet was achieved irrespective of the level of reduction in the packed cell concentrate. However no incidence of NHTFR was noted in n 500 transfusions up followed up in both packed cells and platelet concentrate. Conclusions: Reduction of residual leucocytes is important in the preparation of blood components. Utilisation of new generation filters or leuco depletion processes with better performance characteristics may help to reduce specific leukocyte subsets as well as activation of inflammatory system such as cytokines, which will improve the quality of the component prepared.  

Keywords: Packed cells; Platelet concentrate; Leucoreduction; Blood components.