Indian Journal of Maternal-Fetal & Neonatal Medicine

Neonatal Progeroid Syndrome also Known as Weidemann Rautenstrauch Syndrome is an extremely rare genetic disorder characterised by a senile appearing face (old man look) & Pseudohydrocephalus at birth. We describe a patient showing clinical features of Neonatal Progeroid Syndrome.

Keywords: Neonatal Progeroid syndrome; Weidemann Rotenstrauch syndrome; Pseudohydrocephalus; Senile appearing face.

The objective of this review article is to appraise the different infectious causes leading to congenital malformations in a fetus. Apart from being traumatic to the parents, repeat pregnancy losses or having a congenitally malformed baby,it is a great challenge to diagnose and suspect this causes to the physician Literature search in pubmed and google scholar revealed various aspects of this infections. The mode of transfer to the fetus and the degree of the fetal affection depends on various factors like the gestational age of attack of organisms,the virulence of the organisms and the inocullum of the organism. Infection with Rubella,cytomegalovirus, toxoplasma gondi are the main organisms which are associated with congenital malformations in the fetus.this can lead to either a lethal effect or a defective organogenesis in the fetus. This article aims to throw a light on the various infections,their ill effects and mode of transfer to the fetus. Evidence also supports the routes of infection and the gestational age of contracting the infection by the fetus and the factors which determine the outcome of pregnancy after the fetal infections.

Keywords: Rubella; CMV; Toxoplasmosis; Congenital malformations.

The incidence of multiple pregnancy and delivery has increased dramatically over the past 10–15 years in many developed countries of the world. Data for England and Wales show that between 1980 and 1993 the twin maternity rate increased by <“25% and the triplet and higher order maternity rate more than doubled. Similar trends have been reported from developing countries. The majority of these increases have been linked to the use of ovarian stimulants and assisted reproduction techniques, and multiple pregnancy must be considered to be one of the most important adverse outcomes in current methods of infertility treatment. Obstetric complications associated with multiple pregnancy include prenatal screening problems and increased incidence of pregnancy-induced hypertension, antepartum haemorrhage, preterm labour and assisted or surgical delivery. Neonatal problems include low birthweight and increased prevalence of congenital malformations. Compared with singletons, neonatal mortality is seven times higher in twins and >20 times higher in triplets and higher order births. Survivors also suffer higher rates of cerebral palsy and other neurological impairments.This article reviews neonatal complications and management of twins.

Keywords:  Twins; TTTS; TRAP; Thoracopagus.

Objectives: To evaluate the effect of vaginal progesterone in the prolongation of duration of pregnancy in women at high risk of developing preterm labour. Material and Method: This is a prospective case control study carried out in the department of Obstetrics & Gynaecology S.N. Medical College Agra on 100 patients chosen from in patients and outpatient department (50 cases and 50 control). Women with singleton pregnancy having history of preterm labour, uterine malformation, prophylactic cerclage, currently suffering from premature pains were given daily vaginal progesterone 200mg from 24 weeks and discontinued at 34 weeks of gestation. In both groups rate of preterm labour and neonatal outcome was determined. Results: The incidence of preterm labour in progesterone group was 17.8% and in control group 36%, p value is <0.05.  Conclusion: Administration of progesterone in women at high risk developing preterm labour reduces the incidence of preterm labour, neonatal mortality and morbidity and increases baby weight.

 Keywords: Preterm labour; Progesterone.

Motherhood is a dream to be fulfilled with emotional, psychological & physical maturity. Adolescence is a grey zone between paediatrics & gynaecology. Adolescent pregnancy is a child born to a child who is not mature & will not be able to look after another life at this tender age. Throughout the world, pregnancy & child bearing are occurring at younger ages than in the past; resulting in adverse health, demographic & social consequences. Adolescent child bearing is usually inconsistent with main stream societal demands for attaining adulthood through education, work experience & financial stability. Adolescent pregnancy is a complex issue affecting families, health care professionals, educators & youth themselves. In this article, effect of adolescent pregnancy on maternal, neonatal & child health is analysed. Recent data is provided on adolescent sexuality, contraceptive use, childbearing as well as prevention in communities & clinical practice. 

Keywords: Adolescent pregnancy; Consequences; Prevention; Antenatal care; Prevention; Nutrition.

The analysis of obstetric cases in 2013 in a rural medical college proves that there is a significant difference in rural and urban obstetrics. Data of over 10000 deliveries in this hospital in one year shows that maternal mortality in rural area is not high as it was thought. Maternal morbidity is slightly more due to various reasons. Anaemia was common in rural women. Referrals are more but number of women coming to labour room is significantly higher than prelabour admissions. Antenatal care is good but women are reluctant for admission. C S rate is around 25% mostly due to lesser number of trials. Meconium stained liquor and previous scar are commonest indication for C S. There were 250 stillbirths and 256 neonatal deaths. 

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