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Use of Topical Nitroglycerin in aiding Full Thickness Skin Graft take

Ravi Kumar Chittoria, Padmalakshmi Bharathi Mohan, Barath Kumar Singh. P

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Indian Journal of Preventive Medicine 11(1):p 37-38, January – June 2023. | DOI: 10.21088/ijpm.2321.5917.11123.5

How Cite This Article:

Mohan PB, Chittoria RK, Singh PB. Use of topical nitroglycerin in aiding full thickness skin graft take. Indian J Prev Med. 2023;11(1):37-8.

Timeline

Received : December 30, 2022         Accepted : January 16, 2023          Published : February 28, 2023

Abstract

Skin grafting is a technique that has been used to cover wounds since time immemorial. Various factors affect the take of the graft. If graft take is inadequate, it adds to the morbidity of the patient in terms of additional hospital stay, repeat surgery, and chances of loss of the second graft as well. Various methods have been described in aiding the take of the graft. In this article we would like to highlight the use of topical nitroglycerin in improving the take of Full thickness skin graft.


References

  • 1.   Vargas CR, Iorio ML, Lee BT. A systematic review of topical vasodilators for the treatment of intraoperative vasospasm in reconstructive microsurgery. Plast Reconstr Surg. 2015;136(2):411–22.
  • 2.   Kerrigan CL. Skin flap failure: pathophysiology. Plast Reconstr Surg. 1983;72(6):766-77.
  • 3.   Needleman P, Lang S, Johnson EM Jr. Organic nitrates: relationship between biotransformation and rational angina pectoris therapy. J Pharmacol Exp Ther. 1972;181:489.
  • 4.   Rohrich RJ, Cherry GW, Spira M. Enhancement of skin-flap survival using nitroglycerin ointment. Plast Reconstr Surg. 1984;73(6):943-8.
  • 5.   Dunn CL, Brodland DG, Griego RD, Huether MJ, Fazio MJ, Zitelli JA. A single postoperative application of nitroglycerin ointment does not increase survival of cutaneous flaps and grafts. Dermatol Surg. 2000;26(5):425-7.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Mohan PB, Chittoria RK, Singh PB. Use of topical nitroglycerin in aiding full thickness skin graft take. Indian J Prev Med. 2023;11(1):37-8.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
December 30, 2022 January 16, 2023 February 28, 2023

DOI: 10.21088/ijpm.2321.5917.11123.5

Keywords

Full thickness skin graftNitroglycerinGraft take

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Received December 30, 2022
Accepted January 16, 2023
Published February 28, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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