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Prevalence of Mammary Gland Tumors in Bitches in Ludhiana, Punjab, India

Subrat Kumar Dash

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Indian Journal of Biology 11(2):p 81-86, July - December 2024. | DOI: https://doi.org/10.21088/ijb.2394.1391.11224.3

How Cite This Article:

Dash SK. Prevalence of Mammary Gland Tumors in Bitches in Ludhiana, Punjab, India. Indian J Biol. 2024;11(2):81-86.

Timeline

Received : June 01, 2024         Accepted : August 13, 2024          Published : December 12, 2024

Abstract

Ninety five numbers of female dogs with mammary tumors presented at the small animal clinics from different regions of Ludhiana during 2021 to 2023 were investigated for prevalence of the disease. Temperature and respiration rate of tumor bearing bitches were comparable to that of values of healthy dogs but the pulse rate was observed to be significantly (p<0.05) increased in the tumor group. 69.81% of cases presented were observed to be obese. Adult female dogs (5-10 years old) were most frequently affected (54.71%) followed by old aged dogs (>10 years old). Spitz breed accounted for 39.62% of cases presented followed by German shepherd (31.13%), non-descript (16.98%) and Labrador (12.26%). Female dogs from industrial areas are most susceptible to mammary tumors (79.24%). 79.24% of tumors were palpated to be hard and 20.75% are soft. Histopathlogical analysis revealed that 66.03% of tumors were malignant and 33.96% belong to benign group. Our study concluded that mammary tumor in female dogs is an emerging animal health problem and special attention is needed for its prevention and treatment.


References

  • 1.   Barsky S H and Karlin N J. 2006. Mechanisms of disease: breast tumor pathogenesis and the role of the myoepithelial cell. Nature Clinical Practice Oncology 3: 138-51.
  • 2.   Bertini I and Cavallaro G. 2008. Metals in the “omics” world: copper homeostasis and cytochrome c oxidase assembly in a new light. Journal of Biological Inorganic Chemistry 13: 3-14.
  • 3.   Bronden L B, Nielsen S S, Toft N and Kristensen A T. 2010. Data from the Danish veterinary cancer registry on the occurrence and distribution of tumors in dogs in Denmark. Veterinary Record 166: 586-90.
  • 4.   Goldschmidt M, Pena L and Rasotto R. 2011. Classification and grading of canine mammary tumors. Veterinary Pathology 48: 117-31.
  • 5.   Gupta K, Sood N K, Uppal S K, Mohindroo J, Mahajan S, Raghunath M and Singh K. 2012. Epidemiological studies on canine mammary tumor and its relevance for breast cancer studies. IOSR-Journal of Pharmacy 1: 322-33.
  • 6.   Halazonetis T D, Gorgoulis V G and Bartek J. 2008. An oncogene-induced DNA damage model for cancer development. Science 319: 1352-55.
  • 7.   Klopfleisch R, Lenze D, Hummel M and Gruber A. 2010. Metastatic canine mammary carcinomas can be identified by a gene expression profile that partly overlaps with human breast cancer profiles. BMC Cancer 10: 618.
  • 8.   Kumaraguruparan R, Balachandran C, Manohar B M and Nagini S. 2005. Altered oxidant-antioxidant profile in canine mammary tumours. Veterinary Research Communications 29(4): 287-96.
  • 9.   Oliveira L O, Oliveira R T and Loretti A. 2003. Aspectos epidemiologicos da neoplasia mamaria canina. Acta Scientiae Veterinariae 31: 10-10.
  • 10.   Rivera P, Melin M, Biagi T, Fall T, Haggstrom J and Lindblad-Toh K. 2009. Mammary tumor development in dogs is associated with BRCA1 and BRCA2. Cancer Research 69: 8770-74.
  • 11.   Salas Y, Marquez A, Diaz D and Romero L. 2015. Epidemiological study of mammary tumors in female dogs diagnosed during the period 2002- 2012: A growing animal health problem. PLoS ONE 10(5): 1-15.
  • 12.   Sontasa O, Zyogurtcub H and Gurelb A. 2009. Evaluation of clinical and pathological characteristics of 155 canines with mammary tumors: a retrospective study. Archivos de Medicina Veterinaria 41: 53-59.
  • 13.   Vascellaria M, Capelloa K, Carminatoa A, Zanardelloa C, Baionib E and Mutinelli F. 2016. Incidence of mammary tumors in the canine population living in the Veneto region (Northeastern Italy): Risk factors and similarities to human breast cancer. Preventive Veterinary Medicine 126: 183-89.
  • 14.   Wey N, Gutberlet K and Khon B. 2000. Mamma tumore bei der huding: Hormolle abhangigkeit unter besonderer berucksichtigung von 17 Bostradiol und progesteron. Kleintierpraxis 45:19-31.
  • 15.   Yu F L. 2002. 17Beta-estradiol epoxidation as the molecular basis for breast cancer initiation and prevention. Asian Pacific Journal of Clinical Nutrition 11(7): S460-6.

Data Sharing Statement

There are no additional data available.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

Information not provide.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Dash SK. Prevalence of Mammary Gland Tumors in Bitches in Ludhiana, Punjab, India. Indian J Biol. 2024;11(2):81-86.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
June 01, 2024 August 13, 2024 December 12, 2024

DOI: https://doi.org/10.21088/ijb.2394.1391.11224.3

Keywords

Mammary tumorsBitchesPrevalenceLudhiana

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Received June 01, 2024
Accepted August 13, 2024
Published December 12, 2024

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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