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Indian Journal of Obstetrics and Gynecology

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Patterns of Failures in Endometrial Cancer: A Retrospective Analysis

, George John

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Indian Journal of Obstetrics and Gynecology 5(3 (Supplement)):p 318-318, Jul-Sep 2017. | DOI:

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Abstract

Objective: The aim of this study was to assess the pattern offailure of endometrial cancer patients who have undergone treatment in Father Muller Medical College Mangalore Methods and Materials: A retrospective clinicopathologic review of 37 patients with endometrial cancer whounderwent treatment in Father Muller Medical College Mangalore from january 2014 to march 2017 were done.Peritoneal, hematogenous andlymph node recurrences outside retroperitoneal area wereconsidered as distant failures. All patients have undergone surgery +/- adjuvant radiotherapy. Results: Of the 37 patients analysed 10 have suffered recurrence. The recurrence rates for stage I, II and III were 16 %( 3/18), 0(0/2) and 41 %( 7/17) respectively. Of the 10 patients who failed 6(60%) experienced locoregional failure, 3 had distant failure (30%) and 1(10%) had both locoregional and distant failure. The distant failures are seen in stage III endometrial cancer. 27 (72%) of patients have good local and distant control. Conclusion: For patients in the present study excellent local and distant control have been achieved with adjuvant treatment. Distant failure is an important pattern and should be considered a top Priority in an attempt to improve survival in patients with endometrial carcinoma especially for patients with higher stage.

 

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