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Indian Journal of Obstetrics and Gynecology

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Outcome of Carcinoma Cervix Uteri Patients of Older Than 60 Years versus Less Than 60 Year

Anil Kumar Maurya, Lecturer, Radiotherapy Department, Moti Lal Nehru Medical College, Allahabad, Uttar Pradesh 211002, India. , Kesarwani Radha* , Prakash Gyan** , Maurya Anil K.*** , Singh Virendra****

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Indian Journal of Obstetrics and Gynecology 5(4):p 506-512, Oct-Dec 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.5417.11

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Abstract

Aims and Objectives: Elderly patients of carcinoma cervix uteri are increasing in number. Outcome of cervical cancer with relation to age is controversial. We conducted a retrospective analysis in treated patients of carcinoma cervix uteri to investigate characteristics and outcome of patients older than 60 years in comparison to patients younger than 60 years. Materials and Methods: Medical records of 92 patients of carcinoma cervix uteri who had been treated with radiotherapy or radiotherapy combined with chemotherapy from May’2013 to December’2015 were retrospectively analyzed. The patients were divided in to the two age groups: Group I patients older than 60 years and in group II patients younger than 60 years, there were 37 patients in group I and 55 patients in group II. Patient characteristics, treatment and toxicities were evaluated. Results: With a median followup time of 28 months (range 449 months), disease free survival was 51.35% and 40% in group I and II respectively (p value0.565) whereas overall survival was 62.16% and 45.45% in two groups respectively (p value0.414), hence DFS and OS are not statistically significant. However in incidence of anemia and neutropenia there was statistically significant difference between the two groups (p value 0.0222, 0.0096 for anemia and neutropenia respectively). Conclusions: There is no statistically significant difference in outcome of cervical cancer patients older and younger than 60 years is in our study with respect to DFS and OS. Haematological toxicities were found more in patients more than 60 years in comparison to patients younger than 60 years.

 

Keywords: Cervical Cancer; Women Older than 60 Years; Haematological Toxicity. 

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DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.5417.11

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