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Fetomaternal Outcome in Jaundice Complicating Pregnancy

Sonam Parikh , Archish Desai1 , Sonam Parikh2 , Smriti Mishra3 , Shivangi Gondaliya4 , Sejal Patel5 , Nidhi Patel6

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Indian Journal of Obstetrics and Gynecology 8(1):p 9-14, January-March 2020. | DOI: http://dx.doi.org/10.21088/ijog.2321.1636.8120.1

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Archish Desai, Sonam Parikh, Smriti Mishra, et al. Fetomaternal Outcome in Jaundice Complicating Pregnancy. Indian J Obstet Gynecol. 2020;8(1):9–14.

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

28Introduction: Jaundice affects a small share of pregnant women, yet it takes a serious toll on health of both mother and fetus particularly in developing countries like India. Jaundice is responsible for 10% of maternal deaths. Aim: To find out the maternal and fetal outcome in pregnancy complicated with jaundice in a tertiary care hospital. Material and methods: Prospective observational study of fetomaternal outcome included 50 ANC patients with jaundice (Serum bilirubin > 1.2 mg/ dl; SGOT > 40 IU/L; SGPT > 40 IU/L) admitted in SMIMER hospital during January 2018 to December 2018. Parameters like age, socioeconomic status, LFT and Viral markers were recorded. Patients were treated in line with standard protocol and fetomaternal outcome were then studied. Results: Fifty patients had jaundice during pregnancy. The incidence of jaundice was 0.63%. Sixty-eight percent of patients were between 21 and 29 years of age. The most common cause of jaundice in pregnancy was viral hepatitis seen in 52% cases. Maternal mortality was seen in 5 (10%) cases. The common maternal complications were DIC, atonic postpartum hemorrhage, PET, hepatic encephalopathy and multiorgan failure. Perinatal mortality was seen in 16 (32%) cases. Conclusions: Jaundice in pregnancy has adverse fetomaternal outcome. Viral hepatitis is the most common cause of jaundice in pregnancy. Maternal morbidity and mortality increases with rise in serum bilirubin level. Improvement in health awareness, education and regular antepartum checkups, early referrals end in early diagnosis and careful management of jaundice during pregnancy therefore reducing maternal and fetal mortality and morbidity.

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Cite this article

Archish Desai, Sonam Parikh, Smriti Mishra, et al. Fetomaternal Outcome in Jaundice Complicating Pregnancy. Indian J Obstet Gynecol. 2020;8(1):9–14.

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DOI: http://dx.doi.org/10.21088/ijog.2321.1636.8120.1

Keywords

Jaundice; pregnancy; Hepatitis; Morbidity; Mortality.

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