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Dyslipidemia at 12-14 Weeks of Gestation for Predicting Development of Preeclampsia: A Cohort Study

Vandana Nimbargi , Neha Agarwal1 , Vandana Nimbargi2

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Indian Journal of Obstetrics and Gynecology 10(3):p 145-149, July-September 2022. | DOI: http://dx.doi.org/10.21088/ijog.2321.1636.10322.17

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Neha Agarwal, Vandana Nimbargi/Dyslipidemia at 12-14 Weeks of Gestation for Predicting Development of Preeclampsia: A Cohort Study/Indian J Obstet Gynecol. 2022;10(3):145–149

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Abstract

Introduction: Pregnancy is an insulin resistant condition which allows physiologicaldyslipidemia to occur.  This physiological dyslipidemia is essential for allowing fetal growth. However, when dyslipidemia crosses the  physiological range, it predisposes the woman to preeclampsia development. Epigenetic reprogramming of the  cells in the growing fetus increases the cardiovascular and metabolic complications in the adulthood. Material and methods: 330 antenatal patients were included in the study after matching inclusion and exclusion  criteria. Lipid values were tested at 12-14 weeks of gestation and the women were followed up till delivery.  Preeclampsia development was noted in women having deranged lipid values. Results: Of 330 antenatal patients enrolled in the study, 104 patients developed preeclampsia. All preeclampsia  patients had hyperlipidemia in the 1st trimester. Conclusion: Early, cost-effective detection methods, management and timely delivery by outweighing risks of  prematurity in baby and multiorgan failure,eclampsia and ultimately maternal mortality attributed to preeclampsia

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Neha Agarwal, Vandana Nimbargi/Dyslipidemia at 12-14 Weeks of Gestation for Predicting Development of Preeclampsia: A Cohort Study/Indian J Obstet Gynecol. 2022;10(3):145–149

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DOI: http://dx.doi.org/10.21088/ijog.2321.1636.10322.17

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