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Bone Morphogenic Protein: A Short Reveiw

Prachi Nayak, Reader, Department of Oral Pathology & Microbiology, Maharishi Markandeshwar College of Dental Sciences and Research, Mullana, Ambala, Haryana 133207, India. , Prachi Nayak1 , Himanshu Singh2 , Sushruth Nayak3

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Indian Journal of Dental Education 11(2):p 63-68, April-June 2018. | DOI: https://dx.doi.org/10.21088/ijde.0974.6099.11218.5

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Abstract

Bone morphogenic protein (BMP) was first observed by Marshall Urist. Bmp is effective in the process of osteoinduction. BMP belongs to transforming growth factor-b superfamily. BMP is expressed in various oral lesions like osteosarcoma, malignant fibrous histiocytoma and fibrous dysplasia. The BMP’s play an important role in cell growth, its differentiation, apoptosis, preservation of joint integrity, vascular remodeling as well as commencement of fracture healing. The article is aimed at discussing various types of BMP’s, their functions, molecular characteristics and their role in various oral lesions.

Keywords: Bone Morphogenic Protein; Molecular Characteristics; Oral Lesions. 

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DOI: https://dx.doi.org/10.21088/ijde.0974.6099.11218.5

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