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Assessment of Health Related Quality of Life (HRQoL) in Patients with Oromandibular Dystonia

Saurabh Agarwal , Alok Verma1 , Saurabh Agarwal2

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International Journal of Neurology and Neurosurgery 12(1):p 21-26, January-March 2020. | DOI: DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.12120.3

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Alok Verma, Saurabh Agarwal. Assessment of Health Related Quality of Life (HRQoL) in Patients with Oromandibular Dystonia. Int J Neurol Neurosurg. 2020;12(1):21–26.

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Abstract

Objectives: There is paucity of literature regarding health related quality of life in Oromandibular dystonia (OMD) especially from India. This study assessed HRQoL in its global and disease specific aspect by previously validated instruments in patients with OMD. Method: Subjects with OMD as well as age and gender matched healthy controls were enrolled from Movement Disorder OPD and botulinum toxin clinic. Uneducated patient, those could not read questionnaires, cases that had associated other neurological or debilitating systemic disorders, secondary / pediatrics dystonias, pregnancy or received botulinum toxin within 6 months or underwent surgical treatment were excluded from the study. Each patient filled SF-36 ( HRQoL), BDI (Beck Depression Inventory for depression) and Oromandibular dystonia rating (OMDRS for Disease Severity Scale). Results: 42 pts of OMD were enrolled. There was no significant difference in demographic details between patients with OMD and control. Compared with controls, OMD patient group suffered from statistically significant impaired global health related quality of life (SF 36) in all domains (p < 0.05). More than 60% of patients with OMD had depression (compared to <25% of controls) out of whom 11% had moderate to severe depression (compared to 3.6% of controls). 4.7% of OMD patients had minimal severity scale scoring while 76.2% had moderate, 19.1% had severe disease scoring. Conclusion: This study clearly demonstrated that patients with OMD suffered from significant impairment in HRQoL as compared to controls. Higher proportion of patients with OMD suffered from moderate to severe depression compared to their control.

Keywords: OMD = Oromandibular dystonia; HRQoL = Health related quality of life; SF -36 = 36 item short form health survey; BDI = Beck’s depression inventory; BRS: Blepharospasm rating scale; OMDRS = Oromandibular dystonia rating scale

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Cite this article

Alok Verma, Saurabh Agarwal. Assessment of Health Related Quality of Life (HRQoL) in Patients with Oromandibular Dystonia. Int J Neurol Neurosurg. 2020;12(1):21–26.

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DOI: DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.12120.3

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