Kamakshi

Editorial Board Member

Dr. Kamakshi Mehta

  • Address : Postdoctoral Associate, Ophthalmology, University of Pittsburgh School of Medicine, Vision Institute UPMC, United States
  • E-Mail : kam684@pitt.edu

Research Interests :


Introduction


I am Dr. Kamakshi Mehta, a neuroscientist and toxicologist with a strong research background in neurotoxicology, cognitive neuroscience, and vision science. I earned my Ph.D. in Anatomy from the All India Institute of Medical Sciences (AIIMS), New Delhi, where my doctoral work focused on the neurobehavioral and molecular mechanisms underlying chemical- and environment-induced neurotoxicity. My research has centered on how toxic agents disrupt brain function, leading to alterations in cognition, behavior, and neurotransmitter balance. Currently, I am working as a Postdoctoral Associate at the University of Pittsburgh (USA) where my studies explore transcriptional and epigenetic regulatory networks in retinal development. While this research advances our understanding of neural development and degeneration, my broader scientific interest remains in unraveling how toxicants affect the central nervous system and identifying biomarkers and mechanisms of neurotoxicity. My work has systematically examined the effects of heavy metals like Arsenic on the brain and heart highlighting the roles of oxidative stress, inflammation, apoptotic signaling, and neurochemical disruption. By integrating behavioral, biochemical, and molecular approaches, I aim to connect toxicological exposure with its functional consequences. This perspective contributes to identifying early indicators of toxicant-induced neurological dysfunction and developing strategies for risk assessment and prevention. I have published multiple peer-reviewed research articles and presented my findings at several national and international forums. In addition, I actively contribute to the scientific community through peer review and collaborative research. I view editorial and review work as an essential responsibility to maintain rigor, transparency, and progress in the field of toxicology. With this background, I look forward to contributing to the Journal of Forensic Chemistry and Toxicology by supporting its mission to disseminate impactful research and advance the discipline of toxicological sciences.

AFFILIATION


Postdoctoral Associate

Ophthalmology

University of Pittsburgh School of Medicine, Vision Institute UPMC

3550 Terrace St

Pittsburgh

United States

15213

Email : kam684@pitt.edu


RESEARCH IDS



RESEARCH INTERESTS


# Area
1. Neurodegenerative disorder: Stroke (MCAO model)
2. Neurosciences: Molecular neurobiology and Cognitive neurosciences
3. Nutraceutical Research: Use of natural polyphenols (Curcumin, Resveratrol)
4. Retinal development and Epigenetics
5. Toxicology: Arsenic-induced neurotoxicity and cardiotoxicity

PAPERS PUBLISHED


# Article Title Year
1. #Saroj, *#Mehta K, Pandey KK, Kaur B, Kaler S, Dhar P. Arsenic-induced neurocardiac toxicity and protective role of Resveratrol: histopathological and molecular insights. J Mol Histol. 2025 May 20;56(3):160. doi: 10.1007/ s10735-025-10439-x. PMID: 40392359. *Corresponding author, #Equally contributed first authors 2025
2. *Pandey, K.K., *Mehta, K., Kaur, B. and Dhar, P., 2025. Curcumin alleviates arsenic trioxide-induced neural damage in the murine striatal region. Psychopharmacology, 242(3), pp.497-520. * Corresponding author 2025
3. Mehta, K., Daghsni, M., Raeisossadati, R., Xu, Z., Davis, E., Naidich, A., Wang, B., Tao, S., Pi, S., Chen, W. and Kostka, D., 2024. A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis. Cell Reports, 43(6). DOI:https://doi.org/10.1016/j.celrep.2024.114291 2024
4. Lo, J., Mehta, K., Dhillon, A., Huang, Y.K., Luo, Z., Nam, M.H., Al Diri, I. and Chang, K.C., 2023. Therapeutic strategies for glaucoma and optic neuropathies. Molecular aspects of medicine, 94, p.101219 2023
5. Kamakshi Mehta, Deepak Prabhakar Bhagwat, Devraj, Palika Sehgal, Garima Mittal, Kapil Suchal. Vitex negundo protects against cerebral ischemia-reperfusion injury in mouse via attenuating behavioural deficits and oxidative stress damage. Psychopharmacology. 2022 Feb;239(2):573-587. doi: 10.1007/s00213-021-06050-z. Epub 2022 Jan 24 2022
6. Mehta, K., Kaur, B., Pandey, K.K., Dhar, P. and Kaler, S., 2021. Resveratrol protects against inorganic arsenic-induced oxidative damage and cytoarchitectural alterations in female mouse hippocampus. Acta histochemica, 123(7), p.151792 2021
7. Mehta K, Pandey KK, Kaur B, Dhar P, Kaler S. Resveratrol attenuates arsenic-induced cognitive deficits via modulation of Estrogen-NMDAR-BDNF signalling pathway in female mouse hippocampus. Psychopharmacology. 2021 Sep;238(9):2485-502. 2021
8. Mehta, K., Kanojia, R., Jaiswal, A.K. and Millo, T. Voltammetric Approach of Arsenic (Total) Determination in Blood using Sctrace Gold Electrode. Toxicology International. 2021; 27(3&4), pp.211-219. 2021
9. Mehta K, Kaur B, Kumar Pandey K, Kaler S, Dhar P. Curcumin supplementation shows modulatory influence on functional and morphological features of hippocampus in mice subjected to arsenic trioxide exposure. Anatomy and Cell Biology. 2020 Jan;53:e1. https://doi.org/10.5115/acb.18.169. pISSN 2093-3665 2020
10. A K Jaiswal, Aishwarya Thakur, Kamakshi Mehta, Saisha Nayyer, Zahid Ali. Aluminium Poisoning with Analytical aspects and its Management. J Pharm Adv Res, 2020; 3(3): 804-810. e–ISSN: 2581-6160 (Online) 2020
11. Raza K, Singh S, Rani N, Mishra R, Mehta K, Kaler S. Anomalous Innervation of the Median Nerve in the Arm in the Absence of the Musculocutaneous Nerve. Sultan Qaboos University Medical Journal. 2017 Feb;17(1):e106-e108 2017

BOOKS PUBLISHED


# Title Publication Year

BOOK CHAPTERS PUBLISHED


# Chapter Title Book Title Publication Year

ACADEMIC PROFILE


# Examination Passing Year Country
1. Ph.D. 2021 India
2. M.Sc. 2016 India
3. BSc Medical APB 2014 India

EMPLOYMENT DETAILS


# Institution Position Country Service Period
1. University of Pittsburgh Postdoctoral Associate United States 4 years, 2 months, 16 days
2. University of New Mexico Postdoctoral fellow United States 5 years, 0 months, 0 days
Total Period : 9 years, 2 months, 16 days

PAPERS PRESENTED IN CONFERENCES



RESEARCH PROJECTS



MEMBERSHIPS



TRAINING PROGRAMS ATTENDED



HONOURS AWARDS AND DISTINCTIONS



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EVENTS ORGANIZED