Pediatric Education and Research

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Cornelia de Lange syndrome (CdLS) is a rarely seen multisystem developmental disorder syndrome characterized by facial dysmorphia (arched eyebrows, synophrys, depressed nasal bridge, long philtrum, down-turned angles of the mouth), upper-extremity malformations, hirsutism,cardiac defects, growth and cognitive retardation, and gastrointestinal abnormalities. The features of this disorder vary widely among affected individuals and range from relatively mild to severe. We present here a case of newborn with CdLs. 

Key words: Cornelia de Lange syndrome; Facial dysmorphism; Upper- extremity malformations.

Virginia Apgar (7 June 1909– 7 August 1974) was an American physician who specialized in anesthesia. She was a leader in the fields of anesthesiology and effectively founded the field of neonatology. She is best known as the developer of the Apgar test, a method of assessing the health of newborn babies that has drastically reduced infant mortality over the world. 

Keywords: Virginia apgar; Neonatology; Apgar score; Light house. 

Stevens-Johnson syndrome (SJS) is the most severe cutaneous reactions affecting skin and mucosal surfaces in pediatrics. Supportive therapy is the standard of care for SJS. The use of systemic corticosteroids has been controversial. Human intravenous immunoglobulin has been using in a number of autoimmune and cellmediated blistering disorders of the skin. We report a successful used of intravenous immunoglobulin in a child affected with SJS.

Keyword: Stevens-Johnson syndrome; Immunoglobulin; Skin lesion.