International Physiology

Wound healing is an array of planned steps in a sequence which includes inflammation, proliferation and remodelling. Wound healing depends on growth factors, cytokines, interleukins, etc. There is no well-established method that accelerates wound healing. In this article we report how we have managed a case of post traumatic amputation stump who had developed iatrogenic SVC thrombosis, using different regenerative methods like the autologous platelet rich plasma, insulin therapy, prolotherapy, low level laser therapy for augmenting in wound healing. We also successfully managed SVC thrombosis during the hospital course. In this article we also discuss about the role of prolotherapy in wound healing. Key words: amputated stump, prolotherapy, SVC thrombosis, wound healing.

An imbalance of collagen synthesis and degradation is the most common cause of scarring. Onion extract inhibits fibroblast activity, which helps to reduce scar formation. Despite the fact that onion extract is used in a variety of commercial products, the precise molecular mechanisms by which onion extract reduces scar development in the skin are yet unknown. The aim of this study is to evaluate the effectiveness of onion extract gel in improving the scar. Keyword: Scar reduction, Onion extract gel.

Video Dermatoscopy is a non-invasive method that allows the in-vivo evaluation of colours and microstructures of the epidermis, the dermo-epidermal junction, and the papillary dermis not visible to the naked eye using digital device. This technique is useful for clinician to assess pigmentory/non-pigmentory skin lesion, skin malignancies and skin infections. But usage of Video Dermatoscopy in scar management has scanty data. In this case report we are sharing our experience of Video Dermatoscopy role in scar management. Keywords: Scar, Video Dermatoscopy and Assessment tool.