RFP Journal of Dermatology

Background: Topical steroids are the most commonly prescribed topical medications for the treatment of psoriasis, eczema, lichen planus, vitiligo and dermatitis. Abuse of these topical steroids can lead to various adverse effects.

Aims: To study adverse effects of following topical corticosteroids: (a) Betamethasone valerate cream 0.05% (BV) (b) Betamethasone dipropionate cream 0.05% (BD) (c) Clobetasol propionate cream 0.05% (CP).

Methods and materials: Across sectional study of sixty five patients with side effects of topical steroids were studied in department of skin – VD, Tertiary care hospital from Jan 2010 to December 2010.

Statistics and Analysis: Mean, standard deviation

Results: Out of sixty five cases, eleven patients applied Betamethasone valerate 0.05%, three patients applied Betamethasone dipropionate 0.05% and fifty three patients applied Clobetasol propionate 0.05%. Maximum numbers of cases were in age group more than thirty years. Thirty five were male and nineteen were female. In our study the most common condition for which steroid was applied was chronic eczema. The most common side effect was change in skin color on application of Clobetasol propionate 0.05%. The maximum side effects appeared after three months of application of topical steroid.

Conclusion: The most frequently applied steroid was Clobetasol propionate cream 0.05%. The most common condition for which steroid was applied is chronic eczema and adverse effect is hypopigmentation and depigmentation. In most of the patients adverse effects appeared after three months of steroid application.

Keywords: Topical corticosteroids; Side effects; Abuse.

Multidisciplinary team has effectively adapted advanced reconstructive techniques merged with regenerative medicine modalities to improve outcomes. These treatments combine traditional reconstruction measures with regenerative medicine applications and has been termed ‘hybrid reconstructions’. The hybrid reconstruction model aids in maximizing the function while minimizing the disability and morbidity associated with traditional reconstruction.

Keywords: Hybrid reconstructive ladder; Burns; Contracture.

Cyclic application of “negative pressure” results in a superior local enhancement of cutaneous microcirculation with regards to blood flow and consecutive tissue oxygenation. Beyond that, repeated alterations between different levels of “negative pressure” due to cyclic application represent a greater stimulus for remote conditioning effects, indicating a superior local interaction with the underlying tissue. Here we showed the beneficial effect of cyclic Negative Pressure wound Therapy (NPWT) on donor site after skin graft.

Keywords: Skin Graft Donor Site; Cyclic Negative Pressure Wound Therapy.

A twenty five years old male with post traumatic post-surgical lower motor neuron type recovering paraparesis sustained bilateral ischial Grade-IV pressure ulcer. Hybrid reconstruction ladder was applied for the management of pressure ulcer. Here, in our study, we are evaluating the efficacy of hybrid reconstruction ladder in the management of pressure ulcers. This type of reconstruction is being reported first time in the literature.

Keywords: Hybrid reconstruction ladder; Pressure ulcers.

The role of hybrid reconstruction ladderin the treatment of burn wounds has been widely used owing to its role in improving the outcome in terms of wound bed preparation and post trauma scarring. Here, in our study, we are evaluating the efficacy of use ofhybrid reconstruction ladder in the electric burns of scalp.

Keyword: Hybrid Reconstruction Ladder; Electric Burns; Scalp.

Aim: Skin grafting is a commonly done procedure in plastic surgery. One of the complications that the surgeon is worried about is skin graft failure. Various precautions have been described to prevent this complication. We would like to discuss the role of autologous platelet rich plasma in skin grafting.

Methods: Skin grafting was done for the raw area over the back post electrical burns. Intraoperatively, single injection of 2 ml APRP given to the Skin grafts.

Result: The Skin grafts were healthy, with well healed scars.

Conclusions: We proposed that APRP can be used in application of skin grafts. However, large randomized control trials are required for establishing its role.

Keywords: APRP; Skin grafts; Failure.