RFP Journal of Dermatology

Pyoderma gangrenosum is a rare, chronic, sterile,pustular and progressive ulcerative disease with 4 clinical and histological variants named as ulcerative, pustular, bullous and vegetative. Behcet’s disease is a complex of multisystem disease characterized by orogenital ulceration and eye disease as a classic triad with involvement of other systems . BD and PG , both are neutrophilic dermatoses with oral and genital ulcerations having different frequency. The clinical features of mucosal ulcers are different to some degree between the two diseases, but there is a histopathological distinction between PG and BD . Association of BD and PG are rare but do occur . We report here a case of BD who subsequently developed genital ulcerative PG.

Keywords: Pyoderma gangrenosum; Behcet’s disease; Neutrophilic dermatosis; Orogenital ulcers.

Ulcer is a discontinuity in the lining of the skin.it may be acute or long standing. Non healing ulcers are associated with delay in the healing process and a prolonged morbidity for the patient. There are providing wound coverage including flap coverage, skingrafting, temporary substitutes for dressing etc. In this article we have used modified egg membrane by boiling the egg application for healing of wound and have found it to be useful.

Keywords: Modified egg membrane; Non healing ulcer.

Background: Chronic nonhealing ulcers (CNU) are a major health problem worldwide and it is a challenge for treating doctors. The role of Platelet Rich Plasma (PRP) in wound healing is a boon for the patients. PRP introduces the growth factors directly into the wound and fastened healing. Aims: to evaluate the efficacy and safety of PRP in CNU of various etiologies. Materials and Methods: It was prospective interventioal study including 47 patients with 59 CNU of various etiologies. PRP was prepared by manual double spin method and injected into the ulcer. Same procedure was repeated every two week until complete re-epithelization or up to 6 sittings whichever occurred earlier and followed-up after one month. The patients were evaluated for response and adverse events. The ulcer dimensions were measured and photographs were taken before treatment and at every subsequent sitting. Statistical analysis used: mean, standard deviation, z-test Results: The mean age of the patients was 42.11(SD 9.44) years. The mean duration of ulcer was 4.05 months (SD 2.08). The mean duration of healing was 4.9 weeks (SD 2.21). The mean percentage improvement in area and volume of the ulcers was 93.77% (SD 14.27) and 96.83% (SD 7.94) respectively. No adverse events were noted. Conclusion: Conventional therapies can’t provide growth factors which are necessary for the healing process.so, satisfactory healing does not occur in CNU. PRP fastened the healing by increasing rate of induction of granulation tissue without any significant adverse events. It is safe, biocompatible, cost effective, simple office-based procedure.

Keywords: Platelet rich plasma; Chronic non-healing ulcer; Wound.

Crackers or fireworks are an integral part of the celebration of any event and are nice to see and give enjoyment. But if handled with carelessness these may cause severe injury, even death has been reported. Though any part of the body can be injured, hands are commonly involved in such injuries.This study aimed to assess the pattern of hand injuries caused by fireworks among the patients who presented to a tertiary centre of India.

Keywords: Cracker; Hand; Injury; Firework.