Journal of Dermatology

Henoch-Schoenlein purpura (HSP) is a distinct subtype of hypersensitivity
vasculitis with IgA nephropathy as major complication. We report a case of
8-year old male who presented with recurrent HSP and IgA nephtopathy
successfully treated with rituximab leading to complete and sustained remission in skin lesions and renal function.

Keywords: Henoch-Schoenlein purpura; IgA nephropathy; Rituximab.
 

Lichen planopilaris is a primary cicatricial alopecia involving hair follicles
with a lymphocytic inflammatory process destroying the follicles. Clinically it presents with grouped keratotic follicular papules surrounded by erythema. It is classified as classic LPP, frontal fibrosing alopecia (FFA), and Lassueur Graham-Little Piccardi syndrome. Pseudopelade of Brocq (PPB), can be considered as end-stage LPP which leaves clinical appearance of “footprints in the snow” appearance. Scarring alopecia represents a challenge to patients as well as treating dermatologist where early diagnosis is essential as treatment is difficult in late stage disease. Dermatoscopy accompanied by biopsy is indicated in such cases to start the treatment at the earliest. Three cases of lichen planopilaris with different morphologies is presented here.

Keywords: Lichen Planopilaris; Scarring Alopecia; Pseudopelade of Brocq.
 

Background: Dengue fever (DF) is a viral replication which occurs in dandric (langerhens) cells of the skin as early target of infection. Hence 50% DF involes Dermatological Manifestation. Methods: The Diagnosed DF has petechial or Marbilliform skin lesion was noted. Detailed clinical features, laboratory investigations were also recorded. Results: Dermatological involvement of DF was 26(52), had only cutaneous involvement, 11(22%) had muco-cutaneous involvement, 13(26%) had no Dermatological involvement. The distribution of rash was 21(42%) had generalised rash 17(34%) had Truncal 12(24%) had extremities. Rash with or without puritis was 30(60%) were with purities, 20(40%) without puritis. Conclusion: As DF continuous to be one of the commonest causes of acute febrile illness with involvement of skin and mucosa have significant morbidity and mortality. Hence involvement skin could be the early diagnostic value for DF to treat efficiently with all preventive measures.

Keyboard: DF; DHF; Petachae; Elisa Igm; NSI antigen; Muco cutaneous.
 

Background: 150 patients of both sexes aged between 18 to 65 years were studied for different nail diseases to rule out the cause. Method: The patients who were visiting to OPD of Skin with complaint of nails were studied. To confirm the onychomycosis nail samples were processed by direct microscopy of the KOH mount followed by two sets of culture on Sabouraud’s Dextrose Agar and incubated at 25ºC and 37ºC and were examined once a week for a period of 4-6 weeks to look for fungal causative agent. The routine Blood examination were carried out to rule out Anaemia (Hb%), Diabetic mellitus, Esinophilic count.
Results: 58(38.6%) had onychomycosis, 11(7.3%) pseudomonas nail infection, 13(8.6%) acute paronychia, 16(10.6%) periungal verrucae, 4(2.6%) of psoriasis, 7(4.6%) lichen planus, 2(1.3%) alopecia Areata, 5(3.5%) chronic paronychia, 6(4%) longitudinal melanonychia, 7(4.6%) longitudinal Erythronychia, 9(6%) subungualexostosis, 12(8%) digital nail cyst. Conclusion: This pragmatic approach towards nail diseases at different ages, in both sexes will certainly help the physician, dermatologist to treat efficiently because most of the nail diseases are neoplastic and life threatening.

Keywords: Nail; Onychomycosis; Paronychia; Subungual tumor, Melanonychia.
 

Wound is a common problem following burn, trauma or infection. There are various methods to limit the infection and to cover the raw area. But there is no well-established method that accelerates the wound healing rate. Prolotherapy is a technique that involves injecting some irritant locally in the wound that is claimed to hasten the healing. This article highlights the role of prolotherapy in wound bed preparation.

Keywords: Prolotherapy; Wound; Management.