A study was conducted to determine the effect of chitosan on body weight gain and anti microbial activity in swiss albino mice. A total of 12 swiss albino mice were selected and subjected for two dietary supplement with chitosan (200mg & 1gm/ Kg body weight respectively). The experimental trials were conducted for 5 weeks & dietary supplementation of chitosan was given at weekly intervals.The results of the study indicated that there is increase in the body weight gain of mice by every week due to the dietary suplementation of chitosan.Similarly every week faecal samples were collected & subjected for anti microbial activity by estimating E-coli Counts. There was decrease in the E.coli count for every week with the dietary supplementation of Chitosan indicating the growth promoting and antimicrobial activity of Chitosan.

Keywords: Chitosan Dietary Supplementation Body Weight Gain Antimicrobial Activity E Coli Counts.