The present study was aimed at evaluating comparative effect of Erandadi and Rasonadi Decoctions on Amavata. 40 patients of Amavata were randomly selected from the OPD of Meegoda Ayurveda hospital and equally divided into two groups: group A and group B. The group A was treated with Erandadi Decoction (ED), and group B was treated with Rasonadi Decoction (RD) for a period of one month and followed up for a one month. Data were analyzed by SSPS statistical software. The majority of patients of Amavata were female (95%) and in 46–50 age group (52.5%). Clinical features of Amavata were aggravated by cold water (75%), walking (60%) and rainy weather (57.5%) while it was relieved by rest (75%). Considering prakriti, majority of patients had vata-kapha prakriti (60%). ED improved joint pain, tenderness and disturbed sleep in highly significant manner (p<0.001) whereas stiffness, loss of appetite, heaviness and thirst was improved in significant manner (p<0.05). ED improved ESR, pulse rate, WBC and lymphocyte count in highly significant manner (p<0.001). RD improved joint pain, stiffness, tenderness and loss of appetite in highly significant manner (p<0.001) whereas disturbed sleep, heaviness and thirst was improved significantly (p<0.05). RD improved pulse rate, WBC and lymphocyte count in highly significant manner (p<0.001). When comparing the effects of ED and RD, it was evident that RD is more effective over ED in improving subjective as well as objective parameters of Amavata.

Keywords: Amavata; Rheumatoid Arthritis; Rasonadi Decoction; Erandadi Decoction.