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DOI: DOI: https://dx.doi.org/10.21088/ijamy.0974.6986.11418.1

Abstract

  Introduction: Antimicrobial agents are commonly used nowadays for treating various bacterial and fungal infections. But still most of the physicians are unable to treat these infections appropriately due to hindrances like development of resistance, adverse effects, patient affordability etc. Tuttha Drava (Copper sulphate solution) formulation mentioned in Ayurvedic Texts can be an ideal medicine for treating various infectious diseases. Assessment of its antibacterial activity may provide scientific evidence for the study. Method: Tuttha Drava prepared with classical reference was subjected for analytical study and in vitro antibacterial activity by MIC (Minimum inhibitory concentration) method. The formulation was tested against bacteria like Gram + ve Staphylococcus aureus, Streptococcus pyogens, and Gram –ve Pseudomonas auregenosa and Fluconazole as standard for comparison. Results: Tuttha Drava showed a significant zone of inhibition against two strains of bacteria namely Staphylococcus aureus, Streptococcus pyogens. As Tuttha contains Fe (4.39%), Cu (15.74%), S (4.36%) it may contribute to promote positive health and vigour by increasing the immunity, thus making the body resistant against disease causing factors. Conclusion: Tuttha Drava showed a significant antibacterial activity ie Tuttha Drava shows good Minimum inhibitory concentration (MIC) affect on Streptococcus pyogens, Pseudomonas auregenosa. 

Keywords: Tuttha Drava; Antibacterial Activity

Corresponding Author : Vijaykumar S Kotrannavar, Dean for P.G. Studies & Professor, PG Department of Rasashastra & BK, Shri J.G.C.H.S. Ayurvedic Medical College. Ghataprabha, Dist-Belgaum, Karnataka 591321, India