Mukhadooshika affects the beauty as well as personality of the person. The laxanas of Mukhadooshika can be found in the disease “Acne” in contemporary science. Mud (Mruttika) is used for prevention and cure of diseases and maintenance of health. In this clinical trial, Patients between the age group of 17 years to 25 years having the history of Pidaka resembling Shalmali Kantaka, Medo Garbha and one or more other features with the duration of more than two months were included. 30 patients from OPD were selected and divided into two groups i.e. Mrittika Lepa group and Vachadi Lepa group and each group consists of 15 patients. Both the applications were applied for 15 days once a day in evening before sunset. There was significant result in the reduction (p<0.01) of size and numbers of Pidaka by Mruttika Lepa. There was significant reduction in the snigdhata of skin (p<0.01) in Mruttika group compared to Vachadi Lepa. There was significant decrease in vedana of the Pidaka in Mruttika group (p<0.01).  

Keywords: Mruttika Lepa; Vachadi Lepa; Mukhadooshika; Acne.