The disease Sandhigatavata is first described by Acharya Charaka in the name of Sandhigataanila with the symptoms of Shotha which on palpation feels as bag filled with air and Shula on prasarana and Akunchana(on flexion and extension). The disease can be compared in modern paralance with oesteoarthritis, a degenrative joint disease, the symptoms of which are same as Sandhigatavata and usually occurs after the age of 40 years. In the present study total 42 patients with classical signs and symptoms of sandhigatavata were screened from the O.P.D and I.P.D of Kayachikitsa department, IPGT &RA Hospital, Jamnagar, out of which 6 patients left did not enrolled for the study, remaining 36 patients were divided into 3 groups- 1. Group –R- Only Rasnadi Guggulu – dose- 4 pills three times a day (one pill approx 250 mg) (n=12) 2. Group –GR- Guduchyadi Kashaya(dose- 20 gms twice a day) along with Rasnadi Guggulu (n=12) 3. Group- BR- Bala churna( 3 gram three times a day) along with Rasnadi Guggulu (n=12) Anupana - Warm water The duration of treatment for all the three groups was 8 weeks.It was concluded that “GR”therapy group shows 74.15% effect on total cardinal signs and symptoms, whereas “BR” and “R” therapy provided 71.60% and 64.11% improvement respectively on total cardinal signs and symptoms of Sandhigatavata. 

Keywords: Sandhivata; Oesteoarthritis; Rasnadi Guggulu; Guduchyadi kashaya; Bala churna.