Context herbal drug “Rasona pinda Mahan” is a compound formulation having chief ingredient Rasona ( Allium Sativum ) with 24 other ingredients. Following study is based on the reference given by Bhaisajya Ratnavali. It is a well reputed drug since ancient time for the treatment of Amavata( Rheumatoid Arthritis).The drug was given 6-9 gm daily with anupana of warm water or for 45 days.Total 40 cases were selected regardless of their age,sex, socioeconomic consideration but fully satisfying the criteria of diagnosis of Rheumatoid Arthritis in modern medicine & Amvata in Ayurveda.The overall result of clinical trial showed that 60% demonstrated mild to moderate degree of improvement , 17.5 % significant improvement & 22.5% showed no change after clinical trial.

Key Words: Rasona pinda mahan, Amvata, Rheumatoid arthritis.