AbstractFlaps are important part of reconstruction ladder for wounds and defects following trauma, burns, surgery and infection. A keystone flap is a fasciocutaneous perforator flap on the local level. The robust vascularity of perforator flaps, relative ease of technique, quick operative time, good reproducibility, convenience of usage, and local tissue aesthetic similarities are all advantages of the keystone island flap. Platelet rich fibrin matrix (PRFM) is a fibrin matrix gel comprising platelets, leucocytes, cytokines, and circulating stem cells polymerized in a tetra molecular structure. In this article we employed platelet rich fibrin matrix in the wound bed to prompt the adherence of a type 4 keystone flap in a patient with scalp defect post electrical burn.