Background: The neonatal period is the most susceptible phase of life. The aim of this study was to assess the causes and factors associated with neonatal mortality.

Methodology: This study was a Retrospective study of medical records for 2 years (Jan. 2020- Dec. 2021). The age, sex, gestational age, and morbidity and mortality profile of all SNCU admissions in 1 year were determined, and the difference between inborn (those born in Hospital) and outborn (neonates delivered outside and referred) was calculated.

Results: Of the 1600 neonates admitted, 61.5% neonates were males, 57.4% were Inborn and 42.8% were outborn. Approximately, 33.4% were preterm, and renal cardiovascular (20.4%), Neurological disorder (18.6%), and Respiratory related infection (19.1%) were the chief morbidities. The chief causes of mortality were low birth weight with AOR 1.29 (0.836-2.0120), respiratory support that includes O2 with AOR 5.817 (3.367-10.051), CPAP with AOR 4.902 (2.745-8.754), CMV with AOR 4.251(2.184-8.274) and Level of Care with AOR 4.85 (3.102-11.471). This factor was statistically associated with neonatal mortality.

Conclusion: Low birth weight, respiratory support, neonate size, and degree of care were all found to be associated with newborn mortality in this study. As a result, hospitals ought to emphasize enhancing antenatal, intrapartum, and standardized care for newly admitted infants. A prospective study is what we suggest.