Amitraz is a triazapentadiene compound, and is a member of amidine chemical family. It is used as an insecticide and acaricide for controlling red spider mites, leaf mines, scale insects and aphids. In animals, it is used to control tics, mites, lice, and other animal pests. Aim: to study the clinical features, laboratory abnormalities, complications, and outcome of the patients with acute amitraz intoxication. Materials and methods – retrospective analysis of patients of acute amitraz intoxication admitted to rural medical college loni over a period of 2 years (from september 06 to august 08) was done. Result – a total of 83 patients were admitted to our hospital with acute amitraz intoxication (54 males and 29 females). Analysis of the clinical features revealed that patients had following symptoms in decreasing order of frequency: cns depression (83 patients), vomiting (72 patients), bradycardia (26 patients), hypotension (3 patients) and respiratory failure requiring mechanical ventilation (2 patients).Summary & conclusion: the most common clinical feature is cns depression and patients should be watched for signs of impending respiratory failure. Treatment is essentially symptomatic as there is no specific antidote.

Keywords: amitraz, cns depression, respiratory failure.