Abstract Hand is very uncommon site for primary malignant bony tumors. Chondrosarcoma, which can form de novo as a primary lesion or secondarily from malignant transformation of a preexisting benign lesion, like enchondroma, is common in pelvis, proximal femur and proximal humerus and rarely occurs in hand. Biologic behaviour of chondrosarcomas in hand whether primary or secondary, which have similar histologic features as chondrosarcomas located elsewhere is not known, but they are locally aggressive lesion, rarely metastasises and had relatively favorable prognosis. We report here such a rare case of third metacarpal chondrosarcoma, suspected to be a secondary chondrosarcoma due to malignant transformation of a benign lesion, which was successfully treated with ray excision. As pre conversion stages are benign, can be differentiated from malignant lesion on clinicradiologically features and are amenable to salvage surgery, thus regular followup are suggested to prevent conversion of benign lesion to malignant lesion.
Keywords: Chondrosarcoma; Hand; Metacarpal; Tumor