Volume
1, Issue 2, July - December 2015, Pages 95-98
Original Article
Amide Based Mutual Prodrug: Synthesis and Antimicrobial Evaluation
Asif Husain, Aftab Ahmad, Shah Alam Khan, Nadir Islam
*Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard University, New Delhi-110 062, India. **Jeddah Community College, King Abdul Aziz University, Jeddah 21589, Kingdom of Saudi Arabia. ***Department of Pharmacy, Oman Medical C
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An amide-based mutual prodrug (NA-D) was synthesized by condensing nalidixic acid with dapsone with an aim of preparing a useful drug, which could show broad spectrum of antimicrobial activity. Its structure was established on the basis of elemental analysis, 1H NMR and Mass spectral data results. The mutual prodrug (NA-D) was also evaluated for in-vitro antibacterial and antifungal activity.
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