PMS may be present in individuals with family history of depression, postpartum depression in previous pregnancy, mood disorders. In some patients genetic factors, obesity are the causes. Pyridoxine deficiency, calcium deficiency are some of the nutritional deficiency causes. Pyridoxine deficiency is the main factor in PMS. PMS may be due to luteal phase deficiency, which in turn occurs due to progesterone deficiency. Premenstrual changes are burning issue having both the psychiatry and gynaecology related symptoms and adverse social consequences. Detailed interaction and reassurance of the patient goes a long way in reassuring the adolescent girl. 

Keywords: Premenstrual Syndrome; Adolescent Girl; Pyridoxine; Progesterone.